Registration Dossier
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EC number: 234-207-4 | CAS number: 10595-80-9
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Jun 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- 1992
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Batch No.: 0066758
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- Aerobic activated sludge (microorganisms from a domestic waste¬water treatment plant) was supplied by the sewage treatment plant of Rossdorf, Germany.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 102.5 mg/L
- Based on:
- ThOD
- Parameter followed for biodegradation estimation:
- O2 consumption
- Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 62
- Sampling time:
- 28 d
- Details on results:
- The criterion for ready biodegradability under the conditions of a manometric respirometry test is the degradation of the test item of at least 60%, reached within a 10-day window; the 10-day window starts when the degradation of the test item reaches at least 10% degradation. The 10-day windows began on day 7 after application, the mean value was calculated to be 10% biodegradation (ThODNH4). Therefore, the end of the 10-day window was day 17. After correction for the mean biochemical oxygen demand of the inoculum controls the mean biodegradation percentage based on ThODNH4 at the end of the 10-day window was 62%; the criterion of the 10 day window was passed. The mean biodegradation percentage at the end of the 28-day exposure period was 68% (ThODNH4).
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The degradation rate of 2-SEM reached 60% within the 10-day window and after 28 days. Therefore, 2-SEM is considered to be readily biodegradable.
Reference
Description of key information
The degradation rate of 2-SEM reached 60% within the 10-day window and after 28 days. Therefore, 2-SEM is considered to be readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
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