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EC number: 419-740-4 | CAS number: 137658-79-8 CGL 1545
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Based on long-term (chronic) toxicity study data, the product is very likely not harmful to aquatic organisms. No effects occurred within the range of solubility.
Key value for chemical safety assessment
Additional information
No information on long-term toxicity to aquatic invertebrates of the test substance is available. Read-across is performed to structural analogue EC 411-380 -6, for which adequate data is available. Since, the molecular weight and the average maximum diameter of the target test substance EC 419-740-4 is higher compared to the source substance EC 411-38-6 as well the solubility in the daphnia media of the target substance is lower compared to the solubility in the daphnia medium of the source substance, the read-across is considered as absolute worst-case. Due to the lower solubility in the daphnia medium, the higher molecular weight and higher average maximum diameter,
the target test substance EC 419-740-4 is definitely less bioavailabe and the read-across to the source substance EC 411-38-6 is appropriate and worst-case. The detailed read-across-justification is attached to the target study record.
The long-term toxicity of the structural analogue to aquatic invertebrates has been tested in a GLP guideline study according to OECD 211 (BASF SE 2014). The chronic toxicity of the test substance after 21 d of exposure was tested using Daphnia magna. Due to the low solubility of the test substance a saturated solution of 1.5 mg/L (nominal) test substance was used. After 21 d of exposure no significant mortality, reduced reproduction or any other additional significant adverse effects or abnormal behavior were observed in any of the test treatments.
Therefore, the NOEC and the LOEC are determined to be above 1.5 mg/L (saturated solution).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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