Reaction mass of isopentyl salicylate and 2-methylbutyl salicylate

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From May 23rd, 2018 to May 24th, 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

July 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

method according to Siwoloboff

Key result

Boiling pt.:

293.9 °C

Atm. press.:

1 014.2 hPa

Decomposition:

yes

Remarks on result:

other: boiling point: 293.9 ± 2.5ºC

The preliminary study was carried out in order to determine the boiling temperature range of the test item. The average value of an initial boiling point was approximately 295.0 ºC when heated at 10.0 ºC per minute in the range of 50 - 400 ºC.

3 series of boiling point measurements were performed in the temperature ranges: sample 1: 283.0 - 400.0 ºC, sample 2: 288.0 – 400.0 ºC and sample 3: 287.0 - 400.0 ºC. The heating rate was 1.0 ºC/min. Simultaneously with boiling, decomposition process took place – in all three samples change in colour from transparent to tawny was observed. The average value of boiling temperature (value measured) and boiling point (value corrected according to entered barometric pressure) are presented in Table 1.

Table 1. Measured values of the boiling point of Reaction mass of isopentyl salicylate and 2-methylbutyl salicylate

Sample	Atmospheric pressure (hPa)	Boiling point (ºC)
1	1014.2	296.7
2		291.8
3		293.2
Average values ± standard deviations (ºC)		293.9 ± 2.5

Conclusions:

The boiling point of the test item is 293.9 ± 2.5 ºC under atmospheric pressure (1014.2 hPa)

Executive summary:

The determination of the boiling point was carried out according to OECD Guideline for Testing of Chemicals No. 103 " Boiling Point", and according to EEC method A.2, under GLP conditions. A preliminary study was performed in order to determine the boiling temperature range of the test item under atmospheric pressure of 1014.2 hPa. The capillary tube method was used with the BÜCHI Melting Point M-565 apparatus. In the final test, 3 series of boiling point measurements were performed for the test item in the temperature ranges: sample 1: 283.0 - 400.0 ºC, sample 2: 288.0 – 400.0 ºC and sample 3: 287.0 - 400.0ºC. The heating rate was 1.0 °C/min. Simultaneously with boiling, decomposition process took place – in all three samples change in color from transparent to tawny was observed. The boiling point of the test item under atmospheric pressure of 1014.2 hPa is 293.9 ± 2.5 ºC (average value).

Description of key information

Key study. Method according to OECD 103 and EU method A.2, GLP study. The boiling point of the test item under atmospheric pressure of 1014.2 hPa is 293.9 ± 2.5ºC.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

293.9 °C