Registration Dossier
Registration Dossier
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EC number: 219-536-3 | CAS number: 2457-02-5
Endpoint summary
Administrative data
Description of key information
Additional information
Read-across approach
In the assessment of the environmental fate, ecotoxicity and toxicity of strontium bis(2-ethylhexanoate) (CAS: 2457-02-5), a read-across approach from data for the metal cation (strontium) and the organic anion (2-ethylhexanoate) is followed. This read-across strategy is based upon the observation that upon dissolution in aqueous media, strontium bis(2-ethylhexanoate) completely dissociates and only is present in its dissociated form, i.e. as strontium cation and 2-ethylhexanoate anion. Data on the environmental fate, ecotoxicity and toxicity for both transformation products (strontium cation and 2-ethylhexanoate anion) together can therefore be combined in an additive approach to predict the corresponding properties of strontium bis(2-ethylhexanoate).
A detailed justification for the read-across approach is added as a separate document in section 13 of IUCLID.
Upon dissolution and dissociation of strontium bis(2-ethylhexanoate) into the strontium cation and 2-ethylhexanoate anion, both ions will each show the proper (bio)degradation, bioaccumulation and partitioning behaviour in the environment, as reported for the corresponding ion. The environmental fate and behaviour for the strontium cation and 2-ethyl hexanoate anion is predicted to be clearly different from each other, resulting in a different relative distribution over the environmental compartments (water, air, sediment and soil). Because the relative exposure to both constituent ions is hence predicted to be different from the original composition of strontium bis(2-ethylhexanoate), data for the ecotoxicological properties of this substance tested as such are considered less relevant for its effects and risk assessment and a read-across approach from data for both the strontium cation and 2-ethyl hexanoate anion is preferred. The dose additivity approach is used to explain the ecotoxicological effects of strontium bis(2-ethylhexanoate) based on the data for the individual transformation products (strontium cation and 2-ethylhexanoate anion).
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