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Diss Factsheets
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EC number: 273-399-4 | CAS number: 68959-15-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Auto flammability
Administrative data
Link to relevant study record(s)
- Endpoint:
- auto-ignition temperature (liquids)
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- HYPOTHESIS FOR THE ANALOGUE APPROACH
There is a mechanistic reasoning to the read-across. The target substance, citric acid, sodium titanium salt (Tyzor Activate 422) hydrolyses rapidly upon contact with water or moisture. The complete hydrolysis will take place with no significant reaction products other than sodium citrate and hydrated titanium dioxide.
Therefore, read-across from the existing physicochemical studies (partition coefficient) on the source substance is considered as an appropriate adaptation to the standard information requirements of Annex VII of the REACH regulation.
ANALOGUE APPROACH JUSTIFICATION
Physicochemical data shows that the physicochemical profiles of the target and source substance are similar as outlined in the data matrix.
The target substance (Tyzor Activate 422) is hydrolytically unstable. Due to a rapid hydrolysis octanol-water partition coefficient is not technically feasible to test for the target substances. . Thus, partition coefficient n-octanol/water (Log Kow) of citric acid is used to improve the understanding on physico-chemical properties of the target substance. Due to a rapid hydrolysis citric acid data is used to fulfil endpoint requirements of self-ignition temperature.
DATA MATRIX
See IUCLID section 13.2. for data matrix - Reason / purpose for cross-reference:
- read-across source
- Principles of method if other than guideline:
- Information on the method not available.
- GLP compliance:
- not specified
- Key result
- Auto-ignition temperature:
- 1 010 °C
- Atm. press.:
- 760 mm Hg
- Conclusions:
- A self-ignition temperature of 1010°C is reported for citric acid in SIDS dataset. The original reference was not available for review and no further information is available.
Reference
Description of key information
No study available of the target substance.
Self ignition temperature of citric acid (hydrolysis product of the target substance) is 1010 deg. C. at normal atmospheric pressure i.e. 760 mm Hg.
The target substance, citric acid, sodium titanium salt (Tyzor AC420) hydrolyses rapidly upon contact with water or moisture. The complete hydrolysis will take place with no significant reaction products other than sodium citrate and hydrated titanium dioxide.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.