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EC number: 213-924-6 | CAS number: 1067-12-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Explosiveness
Administrative data
Link to relevant study record(s)
- Endpoint:
- explosiveness, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018-04-23 - 2018-06-14
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- UN Manual of Tests and Criteria: Part I: Classification procedures, test methods and criteria relating to explosives of Class 1
- Version / remarks:
- Recommendations on the TRANSPORT OF DANGEROUS GOODS: Manual of Tests and Criteria, 6th edition, New York and Geneva, 2015: Class 1
Class 1 Test series 1 / 2, Test 1(b) / 2(b): Koenen Test
Class 1 Test series 1 / 2, Test 1(c) / 2(c): Time Pressure Test
Class 4, division 4.1: Test series F, Test F.3: Trauzl Test - Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: OECD113
- Version / remarks:
- OECD Test Guideline 113 (1981) Screening Test for Thermal Stability and Stability in Air
- Deviations:
- no
- Principles of method if other than guideline:
- Thermal Stability OECD 113:
In this test, the thermal stability of the test item is investigated by DSC (differential scanning calorimetry) additional. With this method the difference in energy input into the test item and a reference material as a function of temperature is recorded, while the substance and reference material are subjected to the same temperature program. This energy is the energy necessary to establish zero temperature difference between the test item and the reference material. When the sample undergoes a transition involving a change of enthalpy, that change is indicated by an endothermic departure (e.g. melting, boiling) from the base line of the heat flow record. As result, one gets a thermogram in which the transition heat flux is exhibited as a function of the temperature. In this diagram, the onset of the reaction (e.g. decomposition, physical process) as well of the heat-flux of the reaction is shown. - GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Storage conditions: Room temperature (approx. 20 °C), protected from light
- Key result
- Test series:
- UN Test series 1
- Method:
- UN Test 1 (a): UN gap test
- Parameter:
- other: Trauzl test
- Result:
- result is considered "-" (negative)
- Remarks on result:
- other: expansion of 3.4 ml per 10 g in Trauzl test
- Key result
- Test series:
- UN Test series 1
- Method:
- UN Test 1 (b): Koenen test
- Parameter:
- limiting diameter (mm)
- Result:
- result is considered "-" (negative)
- Remarks on result:
- other: test series with a 1.0 mm diameter orifice plate showed no explosion
- Key result
- Test series:
- UN Test series 1
- Method:
- UN Test 1 (c) (i): Time/pressure test
- Parameter:
- other: pressure
- Result:
- result is considered "-" (negative)
- Remarks on result:
- p < 2070 kPa
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The test item does not have to be classified as explosive substance in class 1 according to the UN Transport Regulation and GHS or CLP Regulation EC 1272/2008 Annex 1: 2.1, respectively.
- Executive summary:
Thermal Stability: The test item in closed glass crucibles showed two exothermic effects in the temperature range of 170 – 410 °C, with an overall decomposition energy of -1250 J/g.
Explosive Properties UN Class 1: In the DSC-measurement the energy of the exothermic decomposition of the test item Tris(hydroxymethyl)phosphine oxide (THPO) was above the threshold of - 500 J/g. Therefore, further tests for explosive properties had to be performed.
In the test on explosive properties according to UN Transport Regulation, Test series 1 and 2 (Koenen- and Time-Pressure Test), and Test series F (BAM Trauzl Test) the test item showed no explosive properties.
According to the results of the test on thermal stability and explosive properties, the test item is classified as following:
UN Transport Regulation: The test item does not have to be classified as explosive substance in class 1 according to the UN Transport Regulation.
GHS (CLP Regulation EC 1272/2008: Annex 1: 2.1): The test item does not have to be classified as explosive substance according to GHS or CLP Regulation EC 1272/2008 Annex 1: 2.1, respectively.
Reference
Description of key information
Explosiveness (determined using OECD 113 / UN Manual of Tests and Criteria: Part I; GLP):
- in the DSC-measurement the energy of the exothermic decomposition of the test item Tris(hydroxymethyl)phosphine oxide (THPO) was above the threshold of - 500 J/g;
- in the test on explosive properties according to UN Transport Regulation, Test series 1 and 2 (Koenen- and Time-Pressure Test), and Test series F (BAM Trauzl Test) the substance THPO showed no explosive properties.
Key value for chemical safety assessment
- Explosiveness:
- non explosive
Additional information
The explosive properties of the test material were determined using OECD 113 / UN Manual of Tests and Criteria: Part I.
A reliability score of 1 was assigned, in accordance with the criteria for assigning data quality in line with the principles described by Klimisch (1997).
Justification for classification or non-classification
According to the results of the test on thermal stability and explosive properties, the substance THPO is classified as following:
- UN Transport Regulation: THPO does not have to be classified as explosive substance in class 1 according to the UN Transport Regulation.
- GHS (CLP Regulation EC 1272/2008: Annex 1: 2.1): THPO does not have to be classified as explosive substance according to EU GHS.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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