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Diss Factsheets
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EC number: 200-309-2 | CAS number: 57-06-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Stability in organic solvents and identity of relevant degradation products
Administrative data
Link to relevant study record(s)
- Endpoint:
- stability in organic solvents and identity of relevant degradation products
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Principles of method if other than guideline:
- Allyl Isothiocyanate displays excellent solubility in ethanol.
0.5 ml each of a mixture of Allyl Isothiocyanate and ethanol were mixed thoroughly in sealed bottles and stored for two weeks at 4, 28 or 40°C.
Allyl Isothiocyanate content was measured by Gas Chromatography after one day and again after two weeks of storage.
The sample stored at 4°C was kept in storage until the sixth month, when its composition was analyzed by GC/MS. - GLP compliance:
- not specified
- Specific details on test material used for the study:
- Allyl Isothiocyanate purity: 99.9%
- Test substance stable:
- no
- Transformation products:
- yes
- No.:
- #1
- Conclusions:
- In the presence of ethanol, Allyl Isothiocyanate produced an additional compound (ethyl allyl thiocarbamate), therefore a mixture of teh test item with ethanol is not feasible as basis for a pratical preparation of Allyl Isothiocyanate.
Reference
In the presence of ethanol, Allyl Isothiocyanate decomposed more rapidly. When stored at 40°C, about 15% decomposed in 2 weeks. Even at 4°C, measurement by GC/MS showed that ethyl allyl thiocarbamate had formed over 26% of the surface area after 6 months of storage
Stability of Allyl Isothiocyanate in ethanol:
|
Residual level (%) |
||
Storage temperature |
Initial |
1 day |
2 weeks |
4°C |
100 |
100 |
99.3 |
28°C |
100 |
99.3 |
91.1 |
37°C |
100 |
97.6 |
78.0 |
Description of key information
In the presence of ethanol, Allyl Isothiocyanate produced an additional compound (ethyl allyl thiocarbamate).
Additional information
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