Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 238-430-8 | CAS number: 14450-05-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13 May - 11 Jun 1997
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- GLP guideline study with acceptable restrictions: The difference of extremes of replicate values of the removal of the test chemical is more than 20%. However, as all replicates show biodegradation values of > 60% this differences are considered as negligible.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- yes
- Remarks:
- The difference of extremes of replicate values of the removal of the test chemical is more than 20%
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Pentaerythritol tetraoleate
- EC Number:
- 242-960-5
- EC Name:
- Pentaerythritol tetraoleate
- Cas Number:
- 19321-40-5
- Molecular formula:
- C77H140O8
- IUPAC Name:
- 3-(oleoyloxy)-2,2-bis[(oleoyloxy)methyl]propyl octadec-9-enoate (non-preferred name)
- Details on test material:
- - Name of test material (as cited in study report): Only trade name given.
- Physical state: yellow liquid
- Analytical purity: no data
- Lot/batch No.: N558331
- Storage condition of test material: at room temperature in the dark
- Other: Stable under storage conditions; 77.10% TOC content
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Municipal sewage treatment plant: Waterschap de Maaskant, s'Hertogenbosch, The Netherlands
- Preparation of inoculum for exposure: Before use, the sludge was allowed to settle for at least 30 min and the liquid decanted for use as inoculum at the amount of 10 mL/L of mineral medium.
- Pretreatment: The sludge was kept under continuous aeration until further treatment.
- Initial cell/biomass concentration: From the supernatant of the sludge the heterotrophic microbial colony count was determined to be
6.6 x 10³ cells/mL. - Duration of test (contact time):
- 29 d
Initial test substance concentration
- Initial conc.:
- 15.5 - 15.6 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Mineral medium
- Test temperature: 20 - 21.5 °C
- pH: 7.4 - 7.7
- Aeration of dilution water: The mixture of mineral components, Milli-Q water and inoculum was aerated with CO2-free air overnight to purge the system of CO2.
- Suspended solids concentration: 4.1 g/L
- other: The test solutions were continuously stirred during the test.
TEST SYSTEM
- Culturing apparatus: 2 litre all-glass brown coloured bottles
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: CO2-free air was sparged through the scrubbing solutions at a constant rate.
- Details of trap for CO2: Three CO2-absorbers (bottles filled with 100 ml 0.0125 M Ba(OH)2) were connected in series to the exit air line of each test bottle. The CO2 produced in each test bottle reacted with the barium hydroxide in the gas scrubbing bottle and precipitated out as barium carbonate.
SAMPLING
- Sampling frequency: on day 3, 6, 8, 10, 15, 20, 24, 29
- Sampling method: The amount of CO2 produced was determined by titrating the remaining Ba(OH)2 with 0.05 M standardized HCL. On the 28th
day, the pH of the test suspensions was measured and 1 ml of concentrated HCL was added to each bottle. The bottle were aerated overnight to
drive off CO2 present in the test suspension. The final titration was made on day 29.
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes, 2 replicates
- Toxicity control: yes, 1 replicate
Reference substance
- Reference substance:
- acetic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 71.9 - 99.8
- Sampling time:
- 29 d
BOD5 / COD results
- Results with reference substance:
- Degradation: 74.5% after 8 days, 60% pass level was reached.
Any other information on results incl. tables
Table 1: Percentage biodegradation of test substance, reference substance and toxicity control
Day |
Test Substance (% degradation) |
Reference substance (% degradation) |
Toxicity control (% degradation) |
||
Replicate 1 |
Replicate 2 |
Ø |
|||
3 |
4.4 |
8.6 |
6.5 |
17.2 |
13.1 |
6 |
11.8 |
16.9 |
14.35 |
41.5 |
27.4 |
8 |
38.4 |
49.7 |
44.05 |
74.5 |
56.5 |
10 |
50.4 |
66.9 |
58.65 |
88.7 |
72.9 |
15 |
58.4 |
77.9 |
68.15 |
98.2 |
83.2 |
20 |
66.6 |
83.9 |
75.25 |
102.6 |
87.1 |
24 |
70.2 |
91.2 |
80.7 |
106.5 |
89.3 |
29 |
71.9 |
97.0 |
84.45 |
110.9 |
94.2 |
29 |
71.9 |
99.7 |
85.8 |
112.0 |
95.3 |
29 |
71.9 |
99.8 |
85.85 |
112.0 |
95.7 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- no
- Remarks:
- The difference of extremes of replicate values of the removal of the test chemical is more than 20% on day 24 and 29.
- Interpretation of results:
- readily biodegradable
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.