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EC number: 249-636-2 | CAS number: 29450-45-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 19.05.2004 - 02.06.2004
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Cross-reference
- Reason / purpose for cross-reference:
- read-across source
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- (4-chloro-2-methylphenoxy)acetic acid
- EC Number:
- 202-360-6
- EC Name:
- (4-chloro-2-methylphenoxy)acetic acid
- Cas Number:
- 94-74-6
- Molecular formula:
- C9H9ClO3
- IUPAC Name:
- (4-chloro-2-methylphenoxy)acetic acid
- Reference substance name:
- Water
- EC Number:
- 231-791-2
- EC Name:
- Water
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- water
- Reference substance name:
- 4-chloro-o-cresol
- EC Number:
- 216-381-3
- EC Name:
- 4-chloro-o-cresol
- Cas Number:
- 1570-64-5
- Molecular formula:
- C7H7ClO
- IUPAC Name:
- 4-chloro-2-methylphenol
- Test material form:
- solid
Constituent 1
impurity 1
impurity 2
Results and discussion
Effect concentrations
- Key result
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/kg soil ww
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
Any other information on results incl. tables
RESULTS
Taking into account the obtained results it was assessed that MCPA TECH-NICAL did not cause mortality of earthworms and changes in behavior and appearance of earthworms, in relation to the control, were not observed. After 14 days of the test, decrease of the earthworms weight in all concentrations was observed, because earthworms was not fed during the experiment. Decrease of earthworms weight in relation to the control was not observed. In concentrations 62.5 — 500 mg/kg dry weight of artificial soil, decrease of earthworms weight was smaller than in control but in the highest concentration decrease of earthworms weight was on the same level as in control.
It was found that:
· median lethal concentration causing 50% of mortality of earthworms population (LC50) after 7 and 14 days is above 1000 mg/kg of dry artificial soil,
Applicant's summary and conclusion
- Executive summary:
The methodical basis of the study was OECD Guidelines No 207 and Good Laboratory Practice (GLP).
The scope of the study was to assess the acute toxicity to earthworms and determine the LC50, LC0and LC100values.
The test species was Eisenia fetida, Say. The tested substance in a form of water suspension was introduced into soil in concentrations of 62.5; 125, 250, 500 and 1000 mg/kg (artificial soil dry weight). The test duration was 14 days. The animals were weighed following this time and alive animals were counted.
Taking into account the obtained results it was assessed that MCPA TECHNICAL did not cause mortality of earthworms and changes in behavior and appearance of earthworms in relation to the control were not observed.
After 14 days of the test, decrease of earthworms weight in relation to the control was not observed. In concentrations: 62,5 — 500 mg dry weight of artificial soil decrease of earthworms weight was smaller than in control but in the highest concentration decrease was on the similar level as in control.
Concentration causing 50% mortality of earthworms population (LC50) after 7 and 14 days is above 1000 mg/kg of dry soil.
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