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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Remarks:
intraperitoneal
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
Experimental Toxicity and Metabolism of 1,2,6-Hexanetriol
Author:
Smyth HF et al.
Year:
1969
Bibliographic source:
Toxicol. Applied Pharmacol., 15: 282-86

Materials and methods

GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Hexane-1,2,6-triol
EC Number:
203-424-6
EC Name:
Hexane-1,2,6-triol
Cas Number:
106-69-4
Molecular formula:
C6H14O3
IUPAC Name:
hexane-1,2,6-triol
Test material form:
liquid
Details on test material:
QSAR method by using calculation

Test animals

Species:
rat
Strain:
other: Carworth-Wistar
Sex:
not specified
Details on test animals or test system and environmental conditions:
TEST ANIMALS:
- Strain: Rat / Carworth-Wistar
- Body weigth: Males 90-120 g

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
water
Remarks:
50% solution

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
10 000 mg/kg bw

Applicant's summary and conclusion