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Diss Factsheets
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EC number: 907-242-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1995-11-03 to 1996-02-06
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EWG
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- part 1 (1984)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 38412 part 1
- Version / remarks:
- national guideline DIN 38412 part 1
- Deviations:
- not specified
- Principles of method if other than guideline:
- Method: other: 92/69/EWG
- GLP compliance:
- yes
Test material
- Reference substance name:
- 1-chlorotetradecane
- EC Number:
- 219-368-0
- EC Name:
- 1-chlorotetradecane
- Cas Number:
- 2425-54-9
- Molecular formula:
- C14H29Cl
- IUPAC Name:
- 1-chlorotetradecane
- Test material form:
- liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- The stability of test substance was tested by GC analysis before test begin. The concentration of the stock solution was analysed at test begin and test end.
Test solutions
- Vehicle:
- no
- Details on test solutions:
- 1g/L of the test substance was dissolved in synthetic freshwater and stirred for 18 h. The solution was filtered and the test substance concentration was analysed.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Strain/clone: Daphnia magna straus, Klon 5
- Source: own cultivation
- Feeding during test: no
24 h before test start the parental daphnids were removed, the juveniles (newly hatched overnight) are used in the test.
ACCLIMATION
- Acclimation conditions: M4 Elendt medium
- Type and amount of food: ad libitum
- Feeding frequency: daily
- Health during acclimation (any mortality observed): healthy stock
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 20 +/- 1 °C
- pH:
- 7.8 to 7.9 at the end of test
- Dissolved oxygen:
- 7.6 to 8.2 mg O2/L at test end
- Nominal and measured concentrations:
- 0.0078 mg/L, 0.013 mg/L, 0.022 mg/L, 0.039 mg/L, 0.065 mg/L, 0.117 mg/L (geometric mean of the stock solution 0 h - 48 h)
- Details on test conditions:
- TEST SYSTEM
- Test vessel: circular vessels with 10 mL test solution
- Aeration: no
- No. of organisms per vessel: 5 daphnids/ vessel
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 1
- Biomass loading rate: ~2 mL per daphnid
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: synthetic freshwater (with Ca 2+ and Mg 2+ ions of 2.5 mmol and a ratio of 4:1; ratio of Na+ to K+ ions 10:1)
- Adjustment of pH: no
- Photoperiod: darkness
EFFECT PARAMETERS MEASURED: (im)mobility after 24 h and 48 h - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.11 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other:
- Remarks:
- conf. interval 0.0065 mg/L - 0.12 mg/L
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.065 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 0.12 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 0.12 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- The test substance concentration was found to be not stable over the test period (test substance concentration decreased >20-50%). Therefore a geometric mean of the concentration of stock solution was determined. The test concentrations were calculated from the stock solution.
- Results with reference substance (positive control):
- Tested concentrations: 1.0 mg/L and 2.0 mg/L. After 24 h 30% of the daphnids were immobilized in the test concentration of 1.0 mg/L, and 100 % were immobilized with a test concentration of 2.0 mg/L. The sensitivity of the daphnid is in the normal range and the test is considered to be valid.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The EC50 value after 48 h exposure is 0.11 mg/L. After exposure for 48 h, the highest concentration at which no immobilization (~ 10 %) occurred was, 0.065 mg/L. After exposure for 48 h, the lowest concentration at which 100 % immobilization occurred was, > 0.12 mg/L (the highest concentrations are based on the substance). The highest achieved concentration under the test coditions is 0.12 mg/L (geometric mean). All concentrations are based on the substance.
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