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Diss Factsheets
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EC number: 944-341-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The described study is a guideline study but only the relevant publication is available. However, this publication does not contain sufficient experimental details (i.e. test substance concentrations). Since no toxicity control has been conducted although it was assumed that released cations lead to inactivation of microorganisms, toxic effects to the sludge cannot be ruled out.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- yes
- Remarks:
- neither toxicity control nor substance concentrations indicated
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
not applicable - Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: activated sludge (industrial and domestic, adaption not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Bürrig wastewater treatment
plant (Leverkusen, Germany)
- Measurements: The chemical oxygen demand was determined with test system LCK 314 (Dr. Lange, Düsseldorf, Germany). - Duration of test (contact time):
- 42 d
- Initial conc.:
- 100 mg/L
- Based on:
- other: Concentration of test substance was not specified in the publication. Concentration is based on used OECD Guideline 301F.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST SYSTEM
- Measuring equipment: The test was carried out with the OxiTop Control system (WTW, Weilheim, Germany). - Reference substance:
- benzoic acid, sodium salt
- Preliminary study:
- not applicable
- Test performance:
- During the test on IDS chelates, precipitation of the corresponding heavy metal hydroxide was observed, indicating liberation of free metal ions.
- Parameter:
- % degradation (O2 consumption)
- Value:
- 75
- Sampling time:
- 20 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 85
- Sampling time:
- 28 d
- Results with reference substance:
- Reference substance was degraded (> 50 % after 4 days and > 75 % after 10 days, both based on O2 consumption).
- Validity criteria fulfilled:
- not specified
- Remarks:
- Sufficient experimental details are missing.
- Interpretation of results:
- other: the substance is potentially biodegradable
- Conclusions:
- It was shown that the substance CaIDHA (also known as Ca-IDS) is biodegradable under the test conditions (85 % biodegradation after 28 days, based on O2 consumption).
- Executive summary:
The biodegradation of CaIDHA and other metal complexes of IDHA was investigated according to OECD Guideline 301F (Cokesa et al., 2004). The test was carried out with the OxiTop Control system (WTW, Weilheim, Germany) and monitored for 42 days. Exact substance concentrations were not indicated in the publication.
During the test, precipitation of the corresponding heavy metal hydroxide was observed, indicating liberation of free metal ions. Based on O2 consumption, CaIDHA revealed 85 % degradation after 28 days and is considered as readily biodegradable. No toxicity control has been conducted.
Reference
For the biodegradation test with metal-IDS complexes, equimolar amounts of each metal and IDS were used. The test was monitored over a period of 42 days. It is shows that Fe2-IDS and Ca2-IDS were readily biodegradable, whereas Mn2-IDS and Cu2-IDS revealed 55 and 40% biodegradation after 28 days, respectively.
Discussion
The IDS isomers of the technical mixture are readily biodegradable, according to OECD guideline 301F. Metal-IDS such as Ca2- and Fe2-IDS complexes fulfill the criteria of ready biodegradability. In contrast, Mn2- and Cu2 -IDS revealed only 55 and 40% biodegradation after 28 days,
respectively. A correlation between complex formation constants (pK) and degradation rates was not observed. The pK values of Ca2-, Mn2-, Fe2-, and Cu2-IDS were 6.7, 7.3, 8.2, and 14.3, respectively. The authors presume that metal-IDS complexes were not transported into the cells, since heavy metal precipitation was observed in the medium during biodegradation tests.
Description of key information
It was shown that the substance CaIDHA (also known as Ca-IDS) is biodegradable under the test conditions (85 % biodegradation after 28 days, based on O2 consumption).
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.