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EC number: 303-773-5 | CAS number: 94213-67-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
algae ErC50: 30 mg/L
algae ErC10: 5.2 mg/L
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 30 mg/L
- EC10 or NOEC for freshwater algae:
- 5.2 mg/L
Additional information
In the Klimisch 1GLP study from Kimmel (2013) the toxicity of Sulfosuccinic (FA C16-18/18:1)E, Na/NH4 to Desmodesmus subspicatus was determined in a static 72-Hour Algal Growth Inhibition Test. The test was performed according to OECD 201 and EU Method C.3. The nominal concentrations of the test item of 0.32, 1.0, 3.2, 10, 32 and 100 mg/L were tested in parallel with a control. The measured concentrations of Sulfosuccinic (FA C16-18/18:1)E, Na/NH4 in the test media of the test concentrations of 3.2 to 100 mg test item/L were between 83% to 107% of the nominal values at the start of the test and between 61% to 96% at the end of the test. Thus, the correct dosing of the test item Sulfosuccinic (FA C16-18/18:1)E, Na/NH4 was confirmed. During the test period of 72 hours, a decrease of test item concentration in the test media occurred. The biological results were related to the mean measured test item concentrations (calculated as the geometric means of the concentrations measured at the start and end of the test):, i.e. 2.3, 8.4, 26 and 101 mg/L for nominal test concentrations of the biologically relevant nominal concentrations of 3.2, 10, 32 and 100 mg/L. The algal biomass in the samples was determined by measurement of the algal cell density using an electronic particle counter (Coulter Counter, Model Z2). The measurements were performed at least in duplicate.
The cell density was determined at 0, 24, 48 and 72 hours. The growth of the control cultures fulfilled the validity criteria from OECD 201 (2006). The 72 -hour ErC10 and ErC50 are 5.2 and 30 mg/L based on the mean measured concentrations.
Read across is made from CAS 147993-66 -6 (source) to the substance related to CAS 90268-39-6 (target). Both substances have a similar C-chain distribution but CAS 147993-66-6 has a higher content of unsaturated C18 (C18´) when compared to the substance related to CAS 90268-39-6. For this group, higher degree of unsaturation was associated with higher toxicity of CAS 147993-66-6, CAS 147993-66-6 is the substance showing highest ecotoxicity in the monoester group. For the sake of being conservative read across is made from the more unsaturated substance (CAS 147993-66-6) to the more saturated substance (substance related to 90268-39-6).
This information is considered to be relevant and reliable for the further risk assessment.
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