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EC number: 203-232-2 | CAS number: 104-74-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- Data is from peer reviewed journal
- Qualifier:
- according to guideline
- Guideline:
- other: Refer below principle
- Principles of method if other than guideline:
- Effect of Laurylpyridinium chloride was determined in larvae of M.Mercenaria (Clam) by continuous exposure of chemical.
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- other aquatic crustacea: M.Mercenaria (Clam)
- Details on test organisms:
- TEST ORGANISM
- Common name: quahog
- Age at study initiation (mean and range, SD): larvae
- Food type: a mixture of a flagellated algal food
- Amount: 0.01 ml of packed cell volume per 1-1 culture per day.
- Frequency: Daily - Test type:
- semi-static
- Water media type:
- saltwater
- Total exposure duration:
- 12 d
- Remarks on exposure duration:
- 10 days of continuous exposure
- Hardness:
- No data
- Test temperature:
- No data
- pH:
- No data
- Dissolved oxygen:
- No data
- Salinity:
- No data
- Conductivity:
- No data
- Nominal and measured concentrations:
- 0.0025, 0.005, 0.01, 0.025, 0.05, 0.10, 0.25, 0.50, 1.00, 2.50, 5.00, 10.00 mg/l
- Details on test conditions:
- Details on test conditions
TEST SYSTEM
- Renewal rate of test solution (frequency/flow rate): Renewed in every second days
- Test concentrations: 0.0025, 0.005, 0.01, 0.025, 0.05, 0.10, 0.25, 0.50, 1.00, 2.50, 5.00, 10.00 mg/l - Reference substance (positive control):
- not specified
- Key result
- Duration:
- 12 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 0.05 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Key result
- Duration:
- 12 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 0.25 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Survival
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In long term toxicity to aquatic invertebrates study Low observed effect concentration (LOEC) of test chemical on M.Mercenaria (Clam) larvae was observed to be 0.25 mg/l and 0.050 mg/l based on survival and growth effects respectively for exposure period of 12 days.
- Executive summary:
Long term toxicity test was performed on M.Mercenaria (Clam) larvae.10,000 to 15,000 larvae reared to the straight hinge larval stage. The cultures were fed a mixture of flagellated algal food and continued exposed to the test chemical for 12days. Effects on cultures based on survival and growth was determined.
Based on the results it was concluded that the endpoint for long term toxicity to aquatic invertebrates to test material was found to be LOEC at 0.25 mg/l and 0.050 mg/l concentrations based on survival and growth of M.Mercenaria (Clam) larvae.This LOEC value suggest that the test chemical was toxic to aquatic invertebrates in chronic exposure.
Reference
Description of key information
Long term toxicity test was performed on M.Mercenaria (Clam) larvae.10,000 to 15,000 larvae reared to the straight hinge larval stage. The cultures were fed a mixture of flagellated algal food and continued exposed to the test chemical for 12days. Effects on cultures based on survival and growth was determined.
Based on the results it was concluded that the endpoint for long term toxicity to aquatic invertebrates to test material was found to be LOEC at 0.25 mg/l and 0.050 mg/l concentrations based on survival and growth of M.Mercenaria (Clam) larvae.This LOEC value suggest that the test chemical was toxic to aquatic invertebrates in chronic exposure.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.25 mg/L
Additional information
In a peer reviewed journal study for 21 days was described for two aquatic invertebrates, M.Mercenaria (Clam) and C. Virginica(Oysters) larvae
Long term toxicity test was performed on M.Mercenaria (Clam) larvae.10,000 to 15,000 larvae reared to the straight hinge larval stage. The cultures were fed a mixture of flagellated algal food and continued exposed to the test chemical for 12days. Effects on cultures based on survival and growth was determined.
Based on the results it was concluded that the endpoint for long term toxicity to aquatic invertebrates to test material was found to be LOEC at 0.25 mg/l and 0.050 mg/l concentrations based on survival and growth of M.Mercenaria (Clam) larvae.This LOEC value suggest that the test chemical was toxic to aquatic invertebrates in chronic exposure.
Long term toxicity test was performed on C. Virginica(Oysters) larvae.10,000 to 15,000 larvae reared to the straight hinge larval stage. The cultures were fed a mixture of flagellated algal food and continued exposed to the test chemical for 14 days. Effects on cultures based on survival and growth was determined.
Based on the results it was concluded that the endpoint for long term toxicity to aquatic invertebrates to test material was found to be LOEC at 0.25 mg/l and 0.050 mg/l concentrations based on survival and growth of C. Virginica (Oysters) larvae.This LOEC value suggest that the test chemical was toxic to aquatic invertebrates in chronic exposure. Based on the above effect concentration we can consider the test material to be classiffied as aquatic chronic 3
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