Registration Dossier
Registration Dossier
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EC number: 235-402-7 | CAS number: 12217-80-0
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 96h LC50 of the target chemical was considered to be >1000 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1 000 mg/L
Additional information
The potential of test substance to cause short term toxicity to fish was investigated in three different studies.
The acute fish toxicity of FAT 36152/D was evaluated in accordance with the EEC Directive, Annex V, Part. C.1. corresponding to the OECD-Test guidelines No.203, (1984). In the pretest the LC5o was determinated to be > 1000 ppm. The test concentrations were chosen as: 562 and 1000 ppm. A control was carried out with the reconstituted water. 10 fish per concentration and water control were used in this static system. No abnormal responses of the fish were observed. Hence, based on the findings of the study, the LC 50 after 96 h was found to be >1000 ppm. This study was most recently conducted and considered as a key study.
Short term toxicity of FAT 36152/B to Zebra fish was investigated in a study using the methodology equivalent to OECD Guideline 203. Groups each containing 10 zebra fish were exposed for 96 h to the test substance at 100, 300 and 1000 mg/L. No mortality was observed with any of the test concentrations. Hence, the 96 h LC0, LC50 and LC100 to zebra fish (Danio rerio) were found to be greater than 1000 mg/L (1986).
Short term toxicity of FAT 36152/A to fish was determined in a study conducted according to the methodology equivalent to OECD Guideline 203. Two groups of zebra fish, each containing 10 fish, were exposed to test concentrations of 300 and 1000 mg/L for 96 hours. No mortality was observed with both concentrations. Hence, the 96 h LC0, LC50 and LC100 of zebra fish (Danio rerio) was considered to be greater than 1000 mg/L (1984).
No mortality or adverse effects were reported in the above discussed studies, hence the target chemical was considered to have low toxicity to fish with LC50 >1000 mg/L.
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