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EC number: 236-400-9 | CAS number: 13351-61-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The immobilisation potential of the test item to Daphnia magna was determined in an OECD guideline 202 test. The EC 50 was determined to be 43 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 43 mg/L
Additional information
Key-study
The immobilisation potential of the test item to Daphnia magna was determined in an OECD guideline 202 test. Test compound was tested at 4.3, 9.4, 20.7, 45.5 and 100 mg/L. Control was dilution water without test compound. Potassium chromate was used as a positive control substance at test concentrations of 0.58, 1.0, 1.8, 3.2, and 5.8 mg/L. A static test was conducted for 48 h in glass beakers (50 mL volume). EC10 and EC50 values were calculated by probit analysis. The 24 h and 48 h EC100 values were determined directly from the test results. The EC10 value was determined to be 33 mg/L after 48 h. The EC50 was determined to be 43 mg/L after 48 h (Confidence interval p=95 %: 40-46). The EC100 was determined to be 100 mg/L.
A read across approach was applied in addition for short-term toxicity to aquatic invertebrates using data of symmetrical 2,2-dimethyl-3-(3-methylphenyl)-propanol (CAS 103694 -68 -4) as this substance was considered to show similar ecotoxicological properties as compared to the test item. For further justification please refer to IUCLID section 13.
Read-across
The 48 h acute toxicity of the read across substance 2,2 -dimethyl-3-(3-methylphenyl)-propanol to Daphnia magna was studied under static conditions according to OECD guideline 202. Daphnids were exposed to the test item (CAS 103694-68-4) at nominal concentrations of 1, 5, 10, 15, 25, 37.5 and 50 mg/L. No analytical monitoring was done. Mortality effects were observed during the study. The 48 h EC50 was determined to be 19 mg/L, the EC100 was determined to be 37.5 mg/L and the EC0 was 1 mg/L.
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