Registration Dossier
Registration Dossier
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EC number: 256-032-2 | CAS number: 42978-66-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
TPGDA is acutely harmful to aquatic algae.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 65.9 mg/L
- EC10 or NOEC for freshwater algae:
- 6.6 mg/L
Additional information
Considering the toxicity of Tripropylenglykoldiacrylate (TPGDA, CAS 42978-66-5) to aquatic algae, experimental data are available for fresh water.
A static non-GLP 72 -h test with Desmodesmus subspicatus was conducted according to the German standard DIN 38412 p 9 (similar to OECD 201). The 72-h ErC50 and the 72 -h EC10 were 65.9 and 6.6 mg/L respectively (nominal, BASF AG, 1988, Rep. no.:88/0671).
The substance was dissolved in chremophor (stock solution: 0.1%) prior to testing.
The test concentrations were not analytically verified.
However, the test concentrations are assumed to be stable over the exposure period based on a sufficient water solubility, a low Henry's Law constant (see IUCLID Ch. 5.4.2) and a low adsorption potential (log Kow = 2.7, measured, see IUCLID Ch.4.7; Log Koc = 3, worst-case, estimated, see IUCLID Ch. 5.4.1).
In conclusion, the substance with high probability is acutely harmful to aquatic freshwater algae.
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