Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 931-312-3 | CAS number: 53880-05-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The kinetic data demonstrate that ca. 80% of the substance (i.e. isocyanate groups (-NCO)) react within the first half an hour after spraying. After 1 hour, 97% of the substance has been transformed into a polymer. The various molecules that form IPDI homopolymer, isocyanaurate type, i.e. trimer, pentamer, heptamer, etc. bear at least three NCO-groups. Just before spraying, the substance is mixed with a polyol having usually a molecular weight (MW) of at least 3000 g/mol. The present OH/NCO-ratio is approx. 1. As soon as one NCO-group of the IPDI homopolymer reacted with the polyol a polymer of Mw >3000 is obtained. This polymer bears still NCO groups that will react further with remaining OH-groups of the polyol. Due to this, the major part of IPDI homopolymer has been converted to a Mw > 3000 polymer at a conversion of e.g. 80%. It is known from scientific literature that the reactivity of isocyanates with amines is even higher, i.e. it will take only a few seconds until all NCO groups have reacted. Considering the kinetic data and the available knowledge on transformation pathways it is concluded that the likelihood for direct soil exposure during outdoor spray applications is negligible.
Small amounts of the substance that may eventually reach the soil compartment hydrolyse when getting in contact with pore water. Upon contact with water the diisocyanate groups of IPDI homopolymer, isocyanurate type react by forming amines and CO2. The amines formed react further with unreacted diisocyanate groups of IPDI homopolymer resulting in oligo- and subsequently polyurea components (see hydrolysis studies Feldhues 2007, AQura 2010). The parent substance has an average molecular weight of 893 g / mol (residual monomers are negligible). However, it can be concluded from the structural formulae that the formed polyurea has a molecular weight amounting to multiples of that of the initial oligomers. Polyurea is therefore considered as not bioavailable and non-toxic to soil organisms.
Moreover, risk management measures preventing potential soil exposure are also stipulated for professional uses. Such risk management measures include amongst others housing, sealing of drains/drainages and other critical soil surfaces. The RMM’s prescribed for professional uses will be detailed in the CSA/CSR.
Indirect exposure to soil via air is unlikely due to the high vapour pressure of the substance (extrapolated value at 20 °C is 1.3 E-9 Pa). Indirect exposure via sewage sludge can also be excluded as the substance hydolyses immediately once it reaches the water compartment (see above).
In summary it is concluded that direct and indirect exposure to soil is unlikely to occur. This conclusion is based on the substance specific properties with its specific reaction kinetic and tailored risk management measures.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.