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EC number: 268-083-8 | CAS number: 68002-70-0 This substance is identified by SDA Substance Name: C16-C22 trialkyl glyceride and SDA Reporting Number: 21-001-00.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- Not available
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to OECD Guideline 203. No analytical verification of test concentrations.
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1988
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: 5.1.1 "Acute toxicity for Fish" of the EEC-Directive 79/831
- Deviations:
- no
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Glycerides, C16-C18 and C18 unsatd.
- IUPAC Name:
- Glycerides, C16-C18 and C18 unsatd.
- Details on test material:
- - Name of test material (as cited in study report): Alkali-refined linseed oil (CAS N° 8001-26-1, EC N° 232-278-6). Under the SDA nomenclature, the name of this substance is 'Glycerides, C16-C18 and C18 unsatd.'
- Substance type: Triglycerdes of vegetable origin
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
None
Sampling and analysis
- Analytical monitoring:
- no
- Details on sampling:
- Not applicable
Test solutions
- Vehicle:
- no
- Details on test solutions:
- No data
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- TEST ORGANISM
- Common name: Zebra fish
- Strain: Barachydanio rerio (Teleostei, Cyprinidae)
- Source: West Aquarium GmbH
- Age at study initiation (mean and range, SD): 2 months
ACCLIMATION
- Acclimation conditions: The fish were held together in a glass tank (200 L). Reconstituted water was used as holding water (according to OECD-guideline 203)
- Type and amount of food: Tetra Min(R) Hauptfutter (Art. no. 1004 DN, produced by Tetra-Werke). The amount was regulated according to the actual consumption observed
- Feeding frequency: Twice daily
- Health during acclimation (any mortality observed): All were in good health and condition, no mortality
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Post exposure observation period:
- None
Test conditions
- Hardness:
- No data
- Test temperature:
- Between 21 and 25 °C
- pH:
- 6.0 to 8.5
- Dissolved oxygen:
- >60%
- Salinity:
- No data
- Nominal and measured concentrations:
- 100 and 1,000 mg/L (nominal)
- Details on test conditions:
- TEST SYSTEM
- Test vessel:
- Type (delete if not applicable): closed
- Material, size, headspace, fill volume: length 300 mm, with 200 mm and height 220 mm
- Aeration: an aquarium aerators, brand Optima (Art. no. A 10007, produced by Weltweit GmbH & Co. KG, D- 2081) were used for continuous aeration
- Renewal rate of test solution (frequency/flow rate): no
- No. of organisms per vessel: 10 - Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: None
- Details on results:
- - Mortality of control: no deaths
- Other adverse effects control: none
- Abnormal responses: no - Results with reference substance (positive control):
- Not applicable
- Reported statistics and error estimates:
- None
Any other information on results incl. tables
- Sublethal observations / clinical signs:
None
Applicant's summary and conclusion
- Conclusions:
- Under the test conditions, the 96 h LC0 (Brachydanio rerio) for linseed oil was found to be 1,000 mg/L (based on nominal concentrations).
- Executive summary:
A study was conducted to evaluate lethal effects of linseed oil to Zebra fish (Brachydanio rerio). The test was carried out according to OECD Guideline 203.
Fish were exposed in separate test batches to different concentration (100 and 1,000 mg/L) of the test material in the test medium over a test period of 96 h (each tank with 10 fish). The observations were made at 0, 24, 48, 72 and 96 h for mortality , abnormal symptoms in the swimming behaviour, in visible physiological functions as well as in the outward appearance of the test fish. Fish were considered dead if touching of the caudal peduncle produced no reaction and if no breathing movements could be observed.
Under the test conditions, the 96 h LC0 (Brachydanio rerio) for linseed oil was found to be 1,000 mg/L (based on nominal concentrations).
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