Registration Dossier
Registration Dossier
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EC number: 428-710-1 | CAS number: 207574-76-3
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): ARA Ergolz II, Füllinsdorf/Switzerland
- Duration of test (contact time):
- ca. 28 d
- Initial conc.:
- ca. 100 mg/L
- Based on:
- test mat.
- Reference substance:
- other: sodium benzoate
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- < 10
- Sampling time:
- 28 d
- Details on results:
- Points of degradation plot (test substance):
2 % degradation after 2 d
2 % degradation after 7 d
2 % degradation after 14 d
3 % degradation after 21 d
3 % degradation after 28 d - Results with reference substance:
- Points of degradation plot (reference substance):
47 % degradation after 2 d
71 % degradation after 7 d
81 % degradation after 14 d
85 % degradation after 21 d
88 % degradation after 28 d - Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The test item was found to be not biodegradable within 28 days according to the OECD guideline 301F.
- Executive summary:
Test item was investigated for its ready biodegradability in a '28 -day manometric respirometry test' acc. to the OECD guideline 301F (1992).
The biochemical oxygen demand (BOD) in the test media was within the range of the inoculum controls.
Therefore, test item was found to be not biodegradable under the test conditions within 28 days.
In the toxicity control, no inhibitory effect of test item was observed.
The suitability of the activated sludge was confirmed by appropriate biodegradation of the reference control sodium benzoate.
Reference
Description of key information
Biodegradation in water: screening tests: not biodegradable: 3 % degradation after 28 d: < 10% degradation, parameter O2 consumption
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
Most probably due to insolubility and non bioavailability, no biodegradation could be observed. Further details of evaluation of the P criterion can be found in the PBT assessment (section 8 of the CSR).
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