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EC number: 204-464-7 | CAS number: 121-32-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from may 19, 2011 to september 08, 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- 2010-12-15
- Type of method:
- effusion method: vapour pressure balance
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0.03 Pa
- Remarks on result:
- other: extrapolated value
- Conclusions:
- Vapour pressure of Ethylvanilline is 0.03 Pa at 25°C.
- Executive summary:
The objective of the study (Defitraces, 2011) is to determine the vapour pressure of ETHYLVANILLINE (121-32-4) following the Commission Directive 92/69/EC – Commission Regulation (EC) No. 761/2009 - EC A4 method and OECD Guideline No. 104 (2006).
For determining the vapour pressure, eight methods are proposed in OECD Guideline No. 104 which can be applied in different vapour pressure ranges. For each method, the vapour pressure is determined at various temperatures.
The method used in this study is the Knudsen cell effusion method coupled to a micro-balance.
The quantity of substance leaving a cell per time unit through an aperture of known size is determined under vacuum conditions such that return of substance into the cell is negligible.
The mass of effused vapour is obtained by determining the loss of mass of the Knudsen cell.
As the logarithm of the vapour pressure of a pure substance is a linear function of the inverse of the temperature, the vapour pressure is determined in a limited temperature range.
In this study, the vapour pressure of Ethylvanilline is 0.03 Pa at 25°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- No test substance information, no guideline, secondary litterature.
- Guideline:
- other: no data
- GLP compliance:
- not specified
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- < 0.001 mm Hg
- Remarks on result:
- other: = 0.13 Pa
- Conclusions:
- The vapour pressure of the test item was reported as 20°C at 0.13 Pa.
- Executive summary:
The vapour pressure of the test item was reported as 20°C at 0.13 Pa.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- No test substance information, no guideline, secondary literature, but reference handbook.
- Guideline:
- other: no data
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0.014 Pa
- Conclusions:
- The vapour pressure of the test item was reported as 25°C at 0.0138 Pa.
- Executive summary:
The vapour pressure of the test item was reported as 25°C at 0.0138 Pa in a reference handbook.
Referenceopen allclose all
Observations
The mass of sample weighed was 7.72 mg. The sample was placed in a Knudsen effusion cell with an aperture size of A = 279.9 µm. Then the cell was placed in the apparatus.
Temperature steps at 25, 30, 35°C and then 40° C were made. The step at 25°C was not taken into account.
After the experimentation, the test item remained a white powder. No degradation of the test item was observed.
Results
The vapour pressure of ETHYLVANILLINE (121-32-4) extrapolated at 25°C is 3.0 x 10-2 Pa.
No more data on results.
No more data on results.
Description of key information
The value retained for the vapour pressure is 0.03 Pa at 25°C (key study)
Key value for chemical safety assessment
- Vapour pressure:
- 0.03 Pa
- at the temperature of:
- 25 °C
Additional information
One experimental GLP study (Défitraces, 2011), OECD 104 compliant, was available and was selected as key study. The Vapour pressure value in this study is 0.03 Pa at 25°C. The study was with reliability 1 according to Klimisch scale.
Two other data issue from literature were selected as supporting studies and were with reliability 2.
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