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EC number: 629-721-4 | CAS number: 308062-60-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Dialkyl amines are for the main fraction protonated under ambient conditions. This means that they will sorb strongly to negatively charged surfaces like glassware, soil and sediment constituents. For dialkylamines C16 -18, Kd values were observed ranging from: 2100 to 56000 L/kg for three different types of soil.
Biodegradation is considered to be the main removal mechanism of these substances. The half-life in the different environmental compartments may be influenced by the bioavailability of the substances. No data is available for the determination of the half-life of dialkylamines in soil or sediment. For risk assessment purposes, these values are estimated based on the ready biodegradability of the available fraction and the sorption data as determined in a sorption desorption test. These environmental half-life's should be considered as worst-case values and are not considered to be a realistic reflection of reality.
The Table below summarizes half-lives derived through default values and a simulation study.
Table Summary of degradation rate constants in various (eco)systems based the ready biodegradability of dialkylamines.
(Eco)system |
Method |
|
Surface water (fresh) |
TGD default value |
15 days half-life |
Surface water (fresh) sediment |
TGD default value |
30000 days half-life |
Marine water |
TGD default value |
50 days half-life |
Soils |
TGD default value |
30000 days half-lifea |
aHalf-life of the fraction dissolved in the water phase is expected to in the order of a few days.
Dialkylamines have a short predicted half-life in air but because there are no important releases into the atmosphere and volatilisation is expected to be negligible, this removal mechanism is thought to be of low relevance.
Dialkylamines do not contain hydrolysable covalent bonds. Cleavage of a carbon-nitrogen bond under environmental conditions is only possible with a carbonyl group adjacent to the nitrogen atom.
Direct photolysis of dialkylamines in air/water/soil will most likely not occur, because it does not absorb UV radiation above 290 nm. Photo transformation in air/water/soil is therefore assumed to be negligible. Daylight might however influence the rate of hydrolysis.
Standard OECD 305 tests are technically not feasible with these strongly sorbing degradable substances. In addition is the route of exposure in a standard OECD 305 test unrealistic for these substances because the substance will either be sorbed or degraded. The bioaccumulation potential of dialkylamines was therefore assessed based on a calculated BCF. As indicated before dialkylamines are readily biodegradable and it is therefore unlikely that they will accumulate in the food chain. The log Kow value of 16.52 as calculated for dialkylamine C18 can be considered as a worst-case as low log Kow value. Based on this log Kow value a low bioaccumulation potential is predicted due to the limited bioavailability of the substance. This prediction is expressed in the calculated BCF (EPIsuite v4.0) of 3.162 L/kg.
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