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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
December, 1994
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994
Report date:
1994

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
Qualifier:
according to guideline
Guideline:
EU Method B.1 (Acute Toxicity (Oral))
GLP compliance:
yes (incl. QA statement)
Test type:
acute toxic class method

Test material

Constituent 1
Chemical structure
Reference substance name:
Heptadecafluorooctanesulphonyl fluoride
EC Number:
206-200-6
EC Name:
Heptadecafluorooctanesulphonyl fluoride
Cas Number:
307-35-7
Molecular formula:
C8F18O2S
IUPAC Name:
heptadecafluorooctane-1-sulfonyl fluoride
Details on test material:
Identification: RM90
Description: colorless liquid
Purity: 97.4%
Stability of test: stable under storage conditions
Stability of test article in vehicle: stable for 48hours in water
Storage Conditions: in the original container well closed at room temperature in a ventilated and dry area.

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
water
Remarks:
bi-distilled
Doses:
10mL/kg
No. of animals per sex per dose:
5 males and 5 females
Control animals:
yes

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.
Mortality:
No deaths as a result of treatment with the test article
Clinical signs:
other: No clinical signs of toxicity were observed during the observation period.
Gross pathology:
No organ abnormalities were observed at necropsy.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The DL50 is greater than 2000mg/kg