Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 252-242-3 | CAS number: 34841-35-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Stability:
Phototransformation in air:-
The atmospheric oxidation half-life of 3’-chloropropiophenone was estimated using the level III multimedia model. The substance 3'-chloropropiophenone has got an estimated half-life of 8.8 d and hydroxyl radical reaction rate constant as 0.0000000000018 cm3/molecule-sec at 25 degrees C. Hence it can be inferred that 3'-chloropropiophenone is persistent in air medium and is not easily phototransformed in air.
Hydrolysis:-
The Hydrolysis rate constant of 3’-chloropropiophenone is estimated to be 0.0000000000034138 (3.4138 E-12) cm3/molecule-sec at half life of 37.598 h. The estimated half-life of the substance indicates that the substance is slowly hydrolysable.
Biodegradation:-
Biodegradation in water:-
The half-life period of 3'-chloropropiophenone in water is 38 d and based on this value it can concluded that the substance is not persistent in water medium since the half-life is less than the threshold of 60 days (to qualify the chemical as persistent). Also the diffusion percentage of 3'-chloropropiophenone in water medium is 22%. This coupled with the dilution of water shall result in ready biodegradability of the chemical.
Data is from PBT Profiler:
Media |
Half-Life(days) |
Percent in each medium |
Water |
38 |
22% |
Biodegradation in water and sediment:
Half life period of 3'-chloropropiophenone in water is observed to be 38 d (912 h) while in sediment it is 340 d (8160 h).Based on these half life values of 3'-chloropropiophenone, it is concluded that the chemical is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is no diffusion of the substance in the sediment as evident from the reported data (0% in sediment) and hence persistence in the sediment compartment is not likely to be critical.
Data is from PBT Profiler:
Media |
Half-Life(days) |
Percent in medium |
Water |
38 |
22% |
Sediments |
340 |
0 |
Biodegradation in soil:
The PBT Profiler & EPI Suite has estimated that 3'-chloropropiophenone is expected to be found predominantly in soil and its persistence estimate is based on its availability in this medium. Its half-life in soil, 1800 hrs (75 days). This exceeds the EPA criteria of >= 2 months (and <= 6 months). Therefore, 3'-chloropropiophenone is estimated to be persistent in the soil environment.
Data is from PBT Profiler:
Media |
Half-Life(days) |
Percent in each medium |
Soil |
75 |
75% |
Data is from EPI Suite:
|
Mass Amount (percent) |
Half-Life (hr) |
Emissions (kg/hr) |
soil |
77.5 |
1800 |
1000 |
Bioaccumulation:-
Bioaccumulation is the process by which the chemical concentration in an aquatic organism achieves a level that exceeds that in the water, as a result of chemical uptake through all possible routes of exposure. The relationship between bioaccumulation and bio-concentration is that, chemicals that have the potential to bioconcentrate also have the potential to bioaccumulate. Bioaccumulation is closely related to the Bioconcentration factor (BCF).
The estimated bioconcentration factor (BCF) for 3'-chloropropiophenone is 8.6 which does not exceed the bioconcentration threshold of 1000. Thus it is concluded that 3'-chloropropiophenone is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.
Adsorption/Desorption
Soil Adsorption Coefficient i.e Koc value of 3'-chloropropiophenone was estimated as 164.6 by means of MCI method. This Koc value at 20 degree C is equivalent to 131.68.
Henry's Law constant
Henry's Law states that at a constant temperature, the amount of a given gas that dissolves in a given type and volume of liquid is directly proportional to the partial pressure of that gas in equilibrium with that liquid.
Henrys Law Constant of 3'-chloropropiophenone at 25 deg C is 0.00000459 (4.59E-006) atm m³/mol.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.