Registration Dossier
Registration Dossier
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EC number: 245-524-2 | CAS number: 23251-72-1
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No studies were available on DEA acetate, but 3-hr activated sludge tests on RA2 and RA1 both found no significant effect on respiration rate at 1000 mg/L (the NOEC). In each case, therefore, the 3-hr EC50 was greater than 1000 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
No studies were available on DEA acetate, but the toxicity of two structurally-related substances to microorganisms has been assessed in two reliable guideline studies.
RA1 was incubated at up to 1000 mg/L (1250 mg/L containing 20% water) with activated sludge. No significant inhibitory effect was seen on respiration rate after a 3-hr incubation period. The 3-hr EC20 and EC50 were higher than 1000 mg/L. The NOEC (defined as the EC15) was 1000 mg/L (Peither, 2000b).
A 3-hr respiration inhibition test was conducted in which RA2 was incubated with aerobic activated sludge at nominal concentrations of up to 1000 mg/L. No inhibitory effect on respiration rate was observed. The 3-hr EC20 and EC50 values were thought to be greater than 1000 mg/L on this basis and the NOEC was 1000 mg/L (Grutzner, 1997d).
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