Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 288-306-2 | CAS number: 85711-46-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Not readily biodegradable (according to OECD criteria).
Key value for chemical safety assessment
Additional information
The uvcb compound was tested in an OECD 301 B study where it attained a biodegradation rate of 30 to 40%. Due to the uvcb nature of the compound an in-depth interpretation of the result is not possible because the OECD 301 B test only measures CO2 evolution as sum parameter to measure the rate of degradation. Therefore, representative components have been individually assessed (available experimental data, QSAR calculations) to adequately address their potential for biodegradation.
Fatty Acids:
Exerimental data are available for fatty acid residues
C18, stearic acid, CAS 57 -11 -4:
A disseminated dossier available on the ECHA homepage (accessed on November 2, 2012) stated an experimentally derived degradation value of 72% (OECD 301 B, CO2 evolution) after 28 days.
C18, oleic acid, CAS 112-80-1:
The J-Check database from the Japanese National Institute of Technology and Evaluation (NITE; accessed on May 7, 2013) stated an experimentally derived degradation value of 78% (OECD 301 C) after 28 days.
Matsumoto (1983) investigated the degradation rate of organic constituents in a water sample collected from Tama River in the Tokyo area. The water sample contained fatty acids. A large portion of these fatty acids (99%) degraded during the 29 d period of incubation. The ease of degradation of fatty acids in this study revealed that lower molecular weight n-alkanoic acids (C13 - C19) degraded fastest.
Matsumoto G. (1983), Changes in organic constituents in river water during incubation. Water Res. Vol. 17, No. 12, pp. 1803 - 1810
Further data from the US EPA's HPV webpage (accessed on November 2, 2012) revealed degradation values from 77 to 95%.
The QSAR calculations on two exemplary C18 fatty acids (stearic acid and oleic acid) revealed degradation rates of > 80% (Catalogic) and "readily biodegradable" (Biowin, EPISuite).
In conclusion, it can be stated that the fatty acid components in the uvcb substance are readily biodegradable.
Other components:
For the other components no experimental data are available. The table below lists the single results from the QSAR estimations of representative structures.
| SMILES | Degradation | QSAR model |
| C(CCC(=O)(O))CCCCC1C=CC(CCCCCC)C2C(=O)OC(=O)C12 | 60.21% | Catalogic |
| C(CCC(=O)(O))CCCCC1CCC(CCCCCC)C2C(=O)OC(=O)C12 | 66.22% | Catalogic |
| Ready Biodegradability Prediction from EPISuite |
||
| C(CCC(=O)(O))CCCCC1C=CC(CCCCCC)C2C(=O)OC(=O)C12 | no | EPISuite |
| C(CCC(=O)(O))CCCCC1CCC(CCCCCC)C2C(=O)OC(=O)C12 | no | EPISuite |
For these components Catalogic revealed degradation values of 60.21 and 66.22%, respectively. The BIOWin prediction is "not readily biodegradable".
The three components are expected to be not readily biodegradable. However, it is assumed that at least a partial degradation occurs under environmental conditions.
In conclusion, the uvcb substance (CAS 85711 -46 -2) contains compounds which are readily biodegradable (fatty acid residues). However, a large amount of the components are not expected to be readily biodegradable but at least partially degradable under environmental conditions.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
