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EC number: 249-535-3 | CAS number: 29253-36-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Additional information
Monoisopropylnaphthalene is reported to produce acute toxic effects on fish, daphnia and algae. Results are displayed in the following table.
Test Organism |
Test Method |
Toxicity values [mg/L] |
Reliability |
Source |
Fish |
OECD 203 |
LC50(96 h): 0.74 |
2 |
NITE 2011 |
Daphnia |
OECD 202 |
EC0(48 h): 0.45 EC50(48 h): 0.67 |
1 |
Muckle 2012 |
OECD 202 |
EC0(48 h): no data |
2 |
NITE 2011 |
|
Alga |
OECD 201 |
ErC50 (72 h): 0.25 NOEC (72 h): 0.079 |
2 |
NITE 2011 |
Long-term toxicity studies could only be identified with diisopropylnaphthalene as test substance.
Short-term toxicity to fish
In a study according to OECD TG 203 a 96h-LC50 of 0.74 mg/L was determined.
Long-term toxicity to fish
No data available
Short term toxicity to aquatic invertebrates
In two studies according to OECD TG 202, short-term toxicity to aquatic invertebrates was tested. In one study, the 48h-EC50 and 48h-EC0 were 0.67 and 0.45 mg/L respectively. In the second study only the 48h-EC50 was determined (0.15 mg/L).
Long term toxicity to aquatic invertebrates
For isopropylnaphthalene, no long-term toxicity study to aquatic invertebrates could be identified. Results from diisopropylnaphthalene as supporting substance are used instead.
Two tests on invertebrate reproduction with diisopropylnaphthalene have been identified. With Daphnia magna in freshwater, a NOEC of 0.013 mg/L has been determined in a valid reproduction test according to OECD TG 202, Part 2. Using Acartia tonsa in a reproduction test in sea water, a NOEC of 0.02 mg/L was obtained. Both results are close together. The NOEC for Daphnia is slightly lower and will be used to characterise the long-term aquatic toxicity of isopropylnaphthalene and for derivation of PNEC.
Toxicity to aquatic algae and cyanobacteria
Toxicity of MIPN to aquatic algae and cyanobacteria was tested according to OECD TG 201. A 72h-EC50 value of 0.25 mg/L and a NOEC of 0.79 mg/L were determined.
Toxicity to microorganisms
Toxicity studies to microorganisms with MIPN could not be identified. With DIPN as test substance, three studies are available. Due to limited reporting (secondary literature or short communication in tabular form), the reliability is 4. As results are very similar, they are used in a weight of evidence approach.
In two tests, fresh water species have been employed (Pseudomonas putida, Tetrahymena pyriformis) in a static test. EC10 and EC0 (growth inhibition) were > 0.16 mg/L and >0.15 mg/L respectively. The third test used Vibrio fischeri in salt water measuring luminescence inhibition. The EC50 was > 0.1 mg/L. No effects were observed. Test substance concentrations were limited due to low water solubility of test substance.
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