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EC number: 274-436-7 | CAS number: 70210-39-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: screening test, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 06 May 1993 to 25 June 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
- Qualifier:
- according to guideline
- Guideline:
- ISO 5815 (Water quality - Determination of Biochemical Oxygen Demand after 5 Days (BOD5) - Dilution and Seeding Method)
- Deviations:
- yes
- Remarks:
- Aerate over night after addition of the inoculum
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- OECD Good Laboratory Regulations and the Procedures and Principles of Good Laboratory Praxis in Switzerland
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 287380.26
- Expiration date of the lot/batch: Nov 1997
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature
- Solubility of the test substance in the solvent/vehicle: 50 g/l (in water) - Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, domestic (adaptation not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Seeding water of an urban waste water
- Concentration of sludge: 6 to 800 mg/l - Duration of test (contact time):
- 5 d
- Initial conc.:
- > 6.5 - < 827.9 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Test temperature: 20 ± 1 °C - Reference substance:
- other: D(+) - Glucose (Merck Nr. 8337) / L-Glutamic acid (Merck Nr. 291)
- Remarks:
- tested in a concentration of 20 ml/l.
- Preliminary study:
- None
- Test performance:
- None
- Remarks on result:
- other: data not available.
- Parameter:
- BOD5
- Value:
- 11 mg O2/g test mat.
- Results with reference substance:
- The BOD5 of the reference substance is 205 mg O2/I.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: BOD5
- Conclusions:
- The BOD5 of FAT 92354/A is 11 mg O2/g.
- Executive summary:
The determination of the BOD5 was conducted according to ISO 5815 Second Edition 1989-08-01 (E) guideline and in accordance with GLP. The biochemical oxygen demand of FAT 92354/A is determined by measuring the dissolved oxygen concentration before and after 5 days incubation at 20 °C in different test concentrations diluted in water saturated with dissolved oxygen that contains a seed of microorganisms. The test organism was collected from a seeding water of urban waste water.
The biological oxygen demand (BOD5) of FAT 92354/A was evaluated in the current study. The test substance was tested in concentrations from about 6 to 800 mg/l, while the reference substance D(+)-Glucose / L-Glutamic acid was tested in a concentration of 20 ml/l.
Based on the findings of the study, the BOD5 of FAT 92354/A is 11 mg O2/g while of the reference substance is 205 mg O2/l.
- Endpoint:
- biodegradation in water: screening test, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: EEC Directive 84/449 (1984), Part. C.9 according to DEV H 41-1, Deutsches Einheits-Verfahren, 1980
- Deviations:
- yes
- Remarks:
- Mean of 2 determinations instead of 3
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- OECD Good Laboratory Regulations and the Procedures and Principles of Good Laboratory Praxis in Switzerland.
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 287380.26
- Expiration date of the lot/batch: Nov 1997
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature
- Solubility of the test substance in the solvent/vehicle: 50 g/l (in water) - Oxygen conditions:
- aerobic
- Inoculum or test system:
- not specified
- Details on inoculum:
- Not applicable
- Duration of test (contact time):
- 2 h
- Initial conc.:
- 5 mg/L
- Based on:
- test mat.
- Details on study design:
- None
- Reference substance:
- other: Potassium hydrogen phthalate solution (Merck-Nr. 11769)
- Remarks on result:
- other: data not available.
- Parameter:
- COD
- Value:
- 742 g O2/g test mat.
- Results with reference substance:
- The COD of the reference substance is 198 mg O2/I.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: COD determined
- Conclusions:
- The COD of FAT 92354/A is 742 mg O2/g.
- Executive summary:
The purpose of the study was to determine COD of the test substance as per EEC Directive 84/449 (1984), Part. C.9 according to DEV H 41-1, Deutsches Einheits-Verfahren, 1980 and in accordance with GLP. A pre-determinated amount of the test substance (FAT 92354/A) dissolved in water is oxidized by potassium dichromate in a strong sulphuric acid medium with silver sulphate as a catalyst under reflux for 2 hours. The residual dichromate is determined by titration with standardized ferrous ammonium sulphate. The test substance concentration was tested in 5.0 mg/l. The reference substance was potassium hydrogen phthalate solution was tested in a concentration of 20 ml/l. Based on the findings of the study, the COD of FAT 92354/A is 742 mg O2/g while of the reference substance is 198 mg O2/l.
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 May 1993 to 17 September 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- Deviations:
- no
- Principles of method if other than guideline:
- Guideline followed
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- OECD Good Laboratory Regulations and the Procedures and Principles of Good Laboratory Praxis in Switzerland
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 287380.26
- Expiration date of the lot/batch: Nov 1997
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature
- Solubility of the test substance in the solvent/vehicle: 50 g/l (in water) - Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: biological sewage treatment plant
- Details on inoculum:
- Strain / Inoculation: Sludge of a biological sewage treatment plant (ARA-Therwil) collected on 01.06.93
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 150 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- Water / Nutrient: according to the specification of the EEC L133 (pp. 99-105) Volume 31 resp. OECD Method 302B.
Temperature: 22.0 ± 3 °C (room temperature)
Test duration: 28 days
Lighting: indirect daylight - Reference substance:
- diethylene glycol
- Parameter:
- % degradation (DOC removal)
- Value:
- 0
- Sampling time:
- 28 d
- Details on results:
- Test substance:
The bioelimination of FAT - 92354/A measured as DOC after 28 days corrected by the blank control is: 0 % (average of 2 tests running in parallel)
Adsorption after 3 hours: 5.6 % - Results with reference substance:
- The bioelimination, corrected by the blank control and measured as DOC (mg/l) is: 99.3 % 26th day
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not inherently biodegradable
- Conclusions:
- The bioelimination of FAT 92354/A observed after 28 days was 0 %.
- Executive summary:
The inherent biodegradability of FAT 92354/A was determined in a 28 days Zahn-Wellens - Test according to OECD Guideline for Testing of Chemicals, No. 302B, Paris 1981 and the EEC-Directive, L133 (pp. 99-105) Volume 31, May 88. The test was performed in compliance with the Good Laboratory Practice (GLP) Regulations of Switzerland. The test substance was tested in concentration of 150 mg/l DOC. The reference substance diethylene glycol was also tested in a concentration of 150 mg/l DOC. Based on the study results, the bioelimination of the test substance (FAT 92354/A) after 28 days was 0 % while of the reference substance after 26 days was 99.3 %.
Referenceopen allclose all
Description of key information
In the studies designated as key, the BOD5 of FAT 92354/A was 11 mg O2/g, while the COD of FAT 92354/A was 742 mg O2/g. The resulting BOD5/COD ratio of 0.015 indicates that this test substance (FAT 91354/A) is not readily biodegradable. In a second study, the BOD5 of FAT 40063/A was 64 mg O2/g, while the COD was 696 mg O2/g and the resulting BOD5/COD calculation which comes to 0.1 also indicates that this test substance (FAT 40063/A) is not biodegradable. The bioelimination of the test substance (FAT 92354/A) after 28 days was 0 % in Zahn Wellens study, while in a second study, the bioelimination of the test substance (FAT 40063/A) after 31 days was 37 %. As a conclusion, the substance is considered to be not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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