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Diss Factsheets
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EC number: 941-992-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Results from the LLNA study OECD 429 and from various OECD 406 studies on BPS do not show skin sensitizing potential on pigs and mice tested.1 2 3
No data are available on the salified phenol sulfonic acid, benzenesulfonic acid, 4-hydroxy-, sodium salt (1:1), CAS 825-90-1.4
Data on salified sulphonated phenols (similar substances called hydrotropes), can be considered.
A category approach evaluation is available on sodium xylenesulphonate. The estimated irritant property of this substance can be helpful (in read across as well) to understand the irritant property of sodium sulphonated phenols, part of the intermediate DCB 58%.Sodium xylenesulphonate is a non skin sensitizer.5
References:
1ECHA Registration Dossier CAS 80-09-1;
2SIDS INITIAL ASSESSMENT PROFILE, CAS 80-09-1, CoCAM 4, 16-18 April 2013;
3EPA, U.S. Environmental Protection Agency, Bisphenol A alternatives in thermal paper, Final Report, January 2014.
4HPV Assessment Report On Hydroxybenzenesulphonic acid CAS No. 1333-39-7, 2004, NOTOX.
5ECHA Registration Dossier, Sodium xylenesulphonate, CAS 1300 -72 -7.
Migrated from Short description of key information:
Skin: non sensitizer
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Skin sensitization
In order to classify the whole mixture for the skin sensitization, the available classification and the results of the reported studies of every known component has been taken into account.
4,4'-sulfonyldiphenol (BPS): non classified
Benzenesulfonic acid, 4-hydroxy-, sodium salt (1:1)- hydrotropes, sodium xylenesulphonate (category approach): non classified
2,4'-sulfonyldiphenol: non classified (C&L ECHA Inventory).
phenol: non classified.
Approximately 48% of the organic part of the intermediate under registration is composed of BPS.
Approximately 14% of the organic part of the mixture is the salified form of the phenol sulfonic acid (p-APS), benzenesulfonic acid, 4-hydroxy-, sodium salt (1:1).
Actually, this substance is completely salified, and therefore, a category approach based on the hydrotropes should be taken into account for a more realistic classification of the whole intermediate mixture DCB, that it is in the neutralized form.2,4'-sulfonyldiphenol is present at 6%, but it is not considered sensitizer.
Phenol is present at concentration of 1.8% (for the evaluation of the skin sensitization potential the presence between 0.01% to 1% shall be taken into account), but it is not classified.
According to the CLP Regulation 1272/2008/EC, 3.4 section, point 3.4.3.3, Table 3.4.5, generic concentration limits shall be used to determine if the mixture is considered to be a non skin sensitizer.
Based on the information available, the intermediate DCB 58% is not classified as a skin sensitizer.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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