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EC number: 260-330-8 | CAS number: 56677-60-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
skin: Tetradecyl chloroformate was found to be irritating to the skin.
eye: Tetradecyl chloroformate was found to be non irritating to the eyes.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
skin irritation:
After application of the test substance to the skin of rabbits, the mean value (24, 48 and 72 h) of the scores of either erythema or edema formation was calculated over all animals tested or for each animal individually.
The mean value for erythema formation was 2.67 (individual animals 2.33, 2.67, and 3.0) over all animals tested.
The mean value for edema formation was 1.33 over all animals tested.The substance is therefore classified as irritating to skin according to EU criteria and as irritating cat. 2 according to GHS criteria. [BASF, 1983]
eye irritation:
The mean scores were 0 for corneal opacity, 0 for iris lesions, 1.78 for redness of the conjunctivae (1.67 for 2/3 and 2 for 1/3 animals), and 0.33 for edema formation (0.33 for the individual rabbits). Thus, the test substance is considered to be non irritating to the eye according to EU and GHS criteria. [BASF, 1983]
Effects on skin irritation/corrosion: irritating
Justification for classification or non-classification
Based on the results obtained in skin irritation studie with rabbits the test substance has to be classified with respect to skin irritation, Xi, R38 according to Directive 67/548/EEC (DSD) and cat. 2, H315 according to Regulation (EC) No 1272/2008 (CLP, GHS).
Based on the results obtained in an eye irritation study with rabbits the test substance has not to be classified with respect to eye irritation according to Directive 67/548/EEC (DSD) and to Regulation (EC) No 1272/2008 (CLP, GHS).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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