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EC number: 700-511-5 | CAS number: 1917-64-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- July 6, 2011 - August 4, 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: This study has been performed in accordance with OECD 301B (1992) and according to GLP principles.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- (1992)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Version / remarks:
- (2008)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: ISO Standard 9439 “Water Quality - Evaluation of ultimate aerobic biodegradability of organic compounds in aqueous medium - carbon dioxide evolution test (1999)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- 5-(methoxymethyl)furan-2-carbaldehyde
- EC Number:
- 700-511-5
- Cas Number:
- 1917-64-2
- Molecular formula:
- C7H8O3
- IUPAC Name:
- 5-(methoxymethyl)furan-2-carbaldehyde
- Details on test material:
- - Name of test material (as cited in study report): MMF
- Description: Clear yellow liquid
- CAS Number: 1917-64-2
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source: The source of test organisms was activated sludge freshly obtained from a municipal sewage treatment plant: 'Waterschap Aa en Maas', 's-Hertogenbosch, The Netherlands, receiving predominantly domestic sewage.
- Treatment: The freshly obtained sludge was kept under continuous aeration until further treatment. The concentration of suspended solids was 4.2 g/l in the concentrated sludge (information obtained from the municipal sewage treatment plant). Before use, the sludge was allowed to settle (60 minutes) and the liquid was decanted for use as inoculum at the amount of 10 ml/l of mineral medium. - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 20 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
Reference substance
- Reference substance:
- acetic acid, sodium salt
- Remarks:
- (40 mg/L)
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 1
- Sampling time:
- 2 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 4
- Sampling time:
- 9 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 4
- Sampling time:
- 14 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 6.5
- Sampling time:
- 19 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 10
- Sampling time:
- 29 d
- Details on results:
- - In the toxicity control more than 25% biodegradation occurred within 14 days (38%, based on ThCO2). Therefore, the test substance was assumed not to inhibit microbial activity.
BOD5 / COD results
- Results with reference substance:
- The positive control substance was biodegraded by 83% within 14 days.
Any other information on results incl. tables
Theoretical CO2 production
- The ThCO2 of MMF was calculated to be 2.20 mg CO2/mg.
- The ThCO2 of sodium acetate was calculated to be 1.07 mg CO2/mg.
pH values
Test medium: |
At the start of the test: |
On day 28: |
Blank control (A) |
7.6 |
7.6 |
Blank control (B) |
7.6 |
7.6 |
Positive control |
7.6 |
7.9 |
MMF (A) |
7.6 |
7.6 |
MMF (B) |
7.6 |
7.6 |
Toxicity control |
7.6 |
7.9 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable under the conditions of the modified Sturm test
- Conclusions:
- In accordance with OECD 301B (1992) and according to GLP principles the ready biodegradability of MMF was investigated. It was determined that MMF is not readily biodegradable under the conditions of the modified Sturm test.
- Executive summary:
In this study the ready biodegradability of MMF was investigated. The study procedures were based on OECD 301B. The test substance was tested in duplicate at 20 mg/l, corresponding to 12 mg TOC/l. Test duration was 28 days (last CO2-measurement on the 29th day). The relative biodegradation values calculated from the measurements performed during the test period revealed 10% biodegradation of MMF in both test bottles. In the toxicity control, MMF was found not to inhibit microbial activity. All the validity criteria were fulfilled. It was determined that MMF is not readily biodegradable under the conditions of the modified Sturm test.
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