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EC number: 500-236-9 | CAS number: 68920-66-1 1 - 2.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28 OCT - 26 NOV 2004
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Niedersächsisches Umweltministerium, Hannover, Germany
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): sewage plant at Hildesheim which comprises mostly municipal sewage and hardly industrial chemical waste.
- Pretreatment: The activated sludge was maintained in an aerobic condition by aeration for four hours and then homogenized with a mixer. The sludge was filtered and the fitrate (30 mL) was subsequently used to initiate inoculum.
- Initial cell/biomass concentration: Colony forming units in the test vessels: 10 exp 5 - 10 exp 6 CFU/L - Duration of test (contact time):
- 28 h
- Initial conc.:
- 20 mg/L
- Based on:
- test mat.
- Initial conc.:
- 2.43 mg/L
- Based on:
- ThOD
- Initial conc.:
- 13.3 mg/L
- Based on:
- TOC
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Mineral nutrient solution according to OECD 301 B
- Test temperature: 20 - 24 °C
- pH: 7.59 - 7.93
TEST SYSTEM
- Culturing apparatus: 5000 mL test vessels (brown glass) filled with 3000 mL test medium
- Number of culture flasks/concentration: 2 - test item, 1 - toxic control, 2 - control
SAMPLING
- Sampling frequency: day 1, 4, 6, 8, 11, 14, 18, 21, 25, 28 and 29
CONTROL AND BLANK SYSTEM
- Inoculum blank: 2 replicates
- Reference control: 1 replicate
- Toxicity control: 1 replicate - Reference substance:
- acetic acid, sodium salt
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 99
- Sampling time:
- 28 d
- Details on results:
- The toxicity control reached 73% biodegradation after 14 days.
- Results with reference substance:
- 87% degradation after 28 days
- Validity criteria fulfilled:
- yes
- Remarks:
- Please refer to table 2 at "Any other information on results incl. tables"
- Interpretation of results:
- readily biodegradable
- Endpoint:
- biodegradation in water: screening tests
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 11 SEP - 23 SEP 1987
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- not specified
- Details on results:
- The result of the study do not allow a statement whether the substance is readily biodegradable or not
- Interpretation of results:
- other: no interpretation of results possible
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 20 SEP - 18 OCT 2004
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): From aeration tank of a municipal waste water treatment plant (ARA Werdhölzli, Zürich), no adapted, not pre-conditioned.
- Pretreatment: Prior the test the sludge was washed twice with tap water.
- Concentration of sludge: 30 mg/L - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Aerobic mineral salts medium prepared with deionised water
- Test temperature: 22 +/- 0.5 °C
- Suspended solids concentration: 30 mg/L
- Continuous darkness: yes, Thermostat cabinet
TEST SYSTEM
- Culturing apparatus: 2500 mL closed glass bottles, containing a total volume of test solution of 2000 mL
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: aeration with CO2-free air, fitted to gas-absorption bottles (containing 125 mL of 0.15 M NaOH)
- Details of trap for CO2 and volatile organics if used: gas-absorption bottles filled with NaOH
SAMPLING
- Sampling frequency: daily
CONTROL AND BLANK SYSTEM
- Inoculum blank: 2 replicates
- Procedure control: 1 replicate
- Abiotic sterile control: no
- Toxicity control: no - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 63
- Sampling time:
- 28 d
- Results with reference substance:
- 77% biodegradation after 14 d
- Interpretation of results:
- readily biodegradable
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1972
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: garden-mould suspension
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): garden-mould suspension (1 mL/L about 10 exp 3 - 10 exp. 5 cells/mL. 100 g garden-mould from the Henkel garden center was given to 1 L tap water, shaken vigorously and filtered through a coarse paper filter, the first 200 mL being discarded.
- Duration of test (contact time):
- 30 d
- Initial conc.:
- 1.84 mg/L
- Based on:
- COD
- Initial conc.:
- 4.6 mg/L
- Based on:
- COD
- Parameter followed for biodegradation estimation:
- O2 consumption
- Parameter:
- % degradation (O2 consumption)
- Value:
- 65 - 96
- Sampling time:
- 30 d
- Interpretation of results:
- readily biodegradable
Referenceopen allclose all
Table 1:
|
Biodegradation (%) |
|||
Day |
6 |
14 |
21 |
28 |
Test substance, |
43 |
81 |
90 |
98 |
Test substance, |
43 |
89 |
100 |
100 |
Functional control 35 mg/L |
48 |
71 |
88 |
100 |
Toxicity control 35 mg/L reference item |
34 |
73 |
81 |
87 |
Table 2: Validity criteria OECD 301 B
Criterion from the guideline |
Outcome |
Validity criterion fulfilled |
Difference of extremes of replicate values of the removal of the test chemical at the plateau, at the end of the test or at the end of the 10-d window, as appropriate, is less than 20%. |
<20% |
yes |
Percentage degradation of the reference compound reached the pass level by day 14 (≥ 60%). |
87% after 14 days. |
yes |
The toxicity control should degrade to at least 35% (based on DOC) or at least 25% (based on ThOD or ThCO2) within 14 d. |
73% after 14 days |
yes |
The IC content of the test substance suspension in the mineral medium at the beginning of the test must be less than 5% of the TC. |
<5% |
yes |
The total CO2 evolution in the inoculum blank at the end of the test should not normally exceed 40 mg/L medium and must be below 70 mg/I. |
46 mg/L |
yes |
Description of key information
Readily biodegradable: 99% in 28 days (OECD 301B)
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Three reliable studies on the ready biodegradability of Alcohols, C16 -18 and C18-unsatd., ethoxylated are available.
The key study was conducted according to OECD guideline 301 B . The study was conducted with a test substance concentration of 20 mg/L and with activated non-adapted sludge as inoculum. Based on CO2 evolution a degradation rate of 99% after 28 days was determined. The results is supported by a study following OECD 301 F. Test medium containing a test substance concentration of 100 mg/L was inoculated with non-adapted activated sludge. After 28 days a degradation rate of 63% was recorded based on O2 consumption of the inoculum.
In a supporting study set up according to OECD 301 D a garden-mould suspension was used as inoculum. A degradation rate of 65 – 96% was determined after 30 days of incubation.
In addition a short summary is available which describes an inherent biodegradation test . However, an interpretation of the results of the study is not possible due to insufficient data reported.
Based on the available test results, Alcohols, C16 -18 and C18 unsatd., ethoxylated is assessed as readily biodegradable according to OECD criteria.
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