Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

No experimental data is available regarding genetic toxicity in vitro of Methyl p-hydroxycinnamate.

Endpoint conclusion
Endpoint conclusion:
no study available

Genetic toxicity in vivo

Description of key information

No experimental data is available regarding genetic toxicity in vivo of Methyl p-hydroxycinnamate.

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

No experimental data is available regarding genetic toxicity (in vitro or in vivo) of Methyl p-hydroxycinnamate . Neither generic mechanism Toolbox profilers (DNA binding by OASIS v.1.3 or DNA binding by OECD) nor specific endpoint Toolbox profilers (DNA alerts for AMES, MN and CA by OASIS v.1.3) give alert for genetic toxicity of Methyl p-hydroxycinnamate. For this reason no classification is proposed for genetic toxicity of Methyl p-hydroxycinnamate (4-HCAME) according to the CLP regulation (EC n. 1272/2008).

Justification for classification or non-classification

No experimental data is available regarding genetic toxicity (in vitro or in vivo) of Methyl p-hydroxycinnamate . Neither generic mechanism Toolbox profilers (DNA binding by OASIS v.1.3 or DNA binding by OECD) nor specific endpoint Toolbox profilers (DNA alerts for AMES, MN and CA by OASIS v.1.3) give alert for genetic toxicity of Methyl p-hydroxycinnamate. For this reason no classification is proposed for genetic toxicity of Methyl p-hydroxycinnamate (4-HCAME) according to the CLP regulation (EC n. 1272/2008).