Decamethyltetrasiloxane

Endpoint summary

Additional information

Reliable data are available describing the toxicity of the registered substance to freshwater fish, invertebrates and algae. Short-term and long-term aquatic toxicity studies are available with the registered substance and freshwater fish. A 96-hour LC₅₀ value of >6.3 μg/L (mortality) and 60-day post-hatch NOEC of ≥7.9 μg/L (hatching, larval survival, abnormal appearance and behaviour) have been determined for the effects of the registered substance on of Oncorhynchus mykiss based on geometric mean measured exposure concentrations and time-weighted average measured concentrations respectively.

A long-term invertebrate study is also available for the registered substance reporting a 21-day NOEC value of ≥4.9 μg/L based on adult mortality, reproduction and growth of Daphnia magna under flow-through conditions and expressed relative to mean measured concentrations. A data waiver is applicable to the short-term toxicity to invertebrates endpoint since long-term data are available.

A 72-hour EC50 value of >2.2 μg/L and NOEC of ≥2.2 μg/L have been determined for the effects of the test substance on growth rate of the freshwater algae Pseudokirchneriella subcapitata. The results are expressed as geometric mean measured concentrations.

An EC50 value of >100 mg/l for toxicity to microorganisms was determined in a reliable ASRI study conducted according to an appropriate test protocol, and in compliance with GLP.