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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to reproduction
Remarks:
other: QSAR
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
1 (reliable without restriction)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other: QSAR
Title:
RBA Multicase
Author:
OECD QSAR Toolbox
Year:
2010
Bibliographic source:
OECD QSAR Toolbox

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 422 (Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test)
Principles of method if other than guideline:
QSAR
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N'-dithiodi-o-phenylenedibenzamide
EC Number:
205-201-9
EC Name:
N,N'-dithiodi-o-phenylenedibenzamide
Cas Number:
135-57-9
Molecular formula:
C26H20N2O2S2
IUPAC Name:
N-{2-[(2-benzamidophenyl)disulfanyl]phenyl}benzamide

Results and discussion

Results: P0 (first parental generation)

Effect levels (P0)

Dose descriptor:
other: QSAR prediction
Effect level:
0 other: %
Based on:
not specified
Sex:
not specified
Remarks on result:
not measured/tested

Results: P1 (second parental generation)

Effect levels (P1)

Dose descriptor:
other: QSAR prediction
Based on:
not specified
Sex:
not specified
Remarks on result:
other: Generation
Remarks:
QSAR prediction (migrated information)

Results: F1 generation

Effect levels (F1)

Dose descriptor:
other: QSAR prediction
Effect level:
0 mg/kg bw/day (nominal)
Sex:
not specified
Basis for effect level:
other: QSAR prediction

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
not toxic to reproduction