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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 700-403-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Sediment toxicity
Administrative data
- Endpoint:
- sediment toxicity: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: SOP E211 based on OSP AR / P ARC OM Protocols on Methods for the Testing of Chemicals Used in the Offshore Industry 2006 Part A: A sediment bioassay using an amphipod Corophium sp.
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Details on test material:
- - Purity: not reported as such
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- Corophium volutator
Study design
- Study type:
- laboratory study
- Test type:
- static
- Water media type:
- saltwater
- Type of sediment:
- natural sediment
Exposure duration
- Duration:
- 10 d
- Exposure phase:
- total exposure duration
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 10 d
- Dose descriptor:
- LC50
- Effect conc.:
- > 12 497 mg/kg sediment dw
- Nominal / measured:
- nominal
- Duration:
- 10 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 6 251 mg/kg sediment dw
- Nominal / measured:
- nominal
Any other information on results incl. tables
The water quality measurements of the test solutions were within acceptable limits during the study.
None of the twenty control Corophium died during the study and this represents an acceptable level of health of the test organisms maintained under test conditions.
Applicant's summary and conclusion
- Conclusions:
- 10-day LC50 of the test substance to Corophium volutator was determined to be > 12497 mg/kg dry sediment.
- Executive summary:
The 10-day LC50 of the test substance to Corophium volutator was determined to be > 12497 mg/kg dry sediment by the non-linear interpolation method in ToxCalc™ Version 5.0.
The highest no-observed effect concentration (NOEC) after 10-days was determined to be 6251 mg/kg dry sediment using Fisher's Exact test in ToxCalc™ Version 5.0.
The water quality measurements of the test solutions were within acceptable limits during the study.
None of the twenty control Corophium died during the study and this represents an acceptable level of health of the test organisms maintained under test conditions.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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