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EC number: 252-961-2 | CAS number: 36306-87-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- other: Inhibition control in Ready Biodegradability test performed according to OECD 301F
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Commercial name: Kephalis
Chemical Nature: 4-(1-ethoxyvinyl)-3,3,5,5-tetramethylcyclohexanone and 1-ethoxy-4-(1-ethoxyvinyl)-3,3,5,5-tetramethylcyclohexanone
Empirical Formula: C14H24O2
Molecular weight: 224.4 g/mol
CAS No.: 36306-87-3
Appearance: pale yellow liquid
Purity: 92.5% (GC, sum of two peaks)
Note:
Please note that although the substance is stated as a mixture of 4-(1-ethoxyvinyl)-3,3,5,5-tetramethylcyclohexanone and 1-ethoxy-4-(1-ethoxyvinyl)-3,3,5,5-tetramethylcyclohex-1-ene in the report, recent analytical data has determined the substance to be a mono-constituent substance (4-(1-ethoxyvinyl)-3,3,5,5-tetramethylcyclohexanone). As the chemical manufacturing process has not changed since the report was written, the recent analytical information is relevant to the batch which was tested (1-ethoxy-4-(1-ethoxyvinyl)-3,3,5,5-tetramethylcyclohex-1-ene is not present in the substance). - Test organisms (species):
- activated sludge, domestic
- Details on inoculum:
- Fresh activated sludge from a biological waste water treatment plant treating predominantly domestic sewage (City of Geneva) was used.
The sludge is collected in the morning, washed three times in the mineral medium (by centrifuging at 1000 g for 10 minutes, discarding the supernatant and resuspending in mineral medium) and kept aerobic until being used on the same day. - Reference substance (positive control):
- yes
- Remarks:
- aniline
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Comparison of respiration of flasks containing test chemical + positive control and flasks containing positive control only
- Details on results:
- The curves obtained with Aniline alone and with Kephalis + aniline show no significant toxic effect of Kephalis on the microorganisms at the test concentration (see illustration section).
- Conclusions:
- The toxicity of Kephalis to microorganism was assessed in an inhibition control of a standardised ready test performed according to OECD 301F. Kephalis did not inhibit the degradation of the positive control, aniline, at a test concentration of 100mg/L. This concentration can be considered the NOEC for the toxicity to STP microorganisms.
Reference
Description of key information
In a standardised ready biodegradability screening study (Givaudan 1996), no toxicity was observed in an inhibition control at a test concentration of 100 mg/L. This concentration can be considered as a NOEC for the toxicity to STP microorganisms.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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