Reaction mass of C18 (unsatd.) fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine ethoxylates, castor oil ethoxylates and sulfosuccinates of C18 (unsatd.) fatty acid diethanolamide, sodium salt

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From December 1, 2014 to January 30, 2015

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

not specified

Type of method:

flask method

Key result

Water solubility:

9.999 g/L

Temp.:

20 °C

pH:

6.4

Following solubilities were determined at different incubation times at 20°C: Incubation time (h) Water solubility [g/L] Average[g/L] 24 9.802 9.999 48 10.018 72 10.178

 

Conclusions:

The water solubility of the test substance at 20°C was determined to be 9.999 g/L.

Executive summary:

A study was conducted to determine the water solubility of the test substance, according to EU Method A.6. About 1.0 g of the test substance was suspended in 100 mL deionised water and stirred in a heated water bath at 30°C for 24, 48, and 72 h, respectively. After incubation, the sample suspensions were cooled to 20°C and kept at this temperature for 24 h without stirring. Afterwards, the samples were centrifuged (3,000 U/min) at 20°C for 15 mins and a second time at 4,000 U/min for 2 h. The still cloudy water phases were filtrated and then analysed by liquid chromatography. Under the study conditions, water solubility of the test substance at a temperature of 20°C was determined to be 9.999 g/L (Seiler, 2015).

Description of key information

The water solubility was determined using flask method, according to EU Method A.6 (Seiler, 2015).

Key value for chemical safety assessment

Water solubility:

9.999 g/L

at the temperature of:

20 °C