Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-745-1 | CAS number: 110-19-0
Specific investigations: other studies
Administrative data
Link to relevant study record(s)
Description of key information
In a respiratory irritation experiment with mice using plethysmographic determination of the respiratory rate, a RD50 (respiratory rate inhibition by 50%) of 3890 mg/m³ was determined for isobutyl acetate (Muller 1984). In the same study RD50 values of 3467 mg/m³ for n-butyl acetate and 5623 mg/m³ for isobutanol were determined. Thus indicating that n-butyl acetate is slightly more irritant than isobutyl acetate and isobutanol being the least irritant of the three substances.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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