Registration Dossier
Registration Dossier
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EC number: 234-456-9 | CAS number: 12004-39-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A key study is provided for the assessment of short-term toxicity to Daphnia. The study was conducted in accordance with GLP and OECD test guidelines with no deviations.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.687 mg/L
Additional information
Key study
The acute toxicity of dialuminium titanium pentaoxide to Daphnia magna was determined in a study carried out in accordance with OECD guideline 202 ''Daphnia sp., Acute Immobilisation Test''. As the test substance is a poorly soluble inorganic compound, test organisms were exposed to test solution prepared at its maximum achievable saturation level. Concentrations of aluminium and titanium were determined by ICP-MS and were then used to calculate equivalent concentrations of the test substance. The loading rate used in the test was 100 mg/L. Test solutions were replaced every 24 hours.
After 48 hours of exposure no immobilisation or abnormal symptoms were observed. The 48hr EC50was determined to be >0.824 mg/L based on aluminium analysis and >0.687 mg/L based on titanium analysis. All validity criteria were met and this study is considered reliable without restriction.
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