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EC number: 293-297-3 | CAS number: 91053-33-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 02-03-2015 to 27-05-2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study performed under GLP. All relevant validity criteria were met.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- inspected March 2013 ; signature: May 2013
- Type of method:
- effusion method: isothermal thermogravimetry
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 35 Pa
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0.27 mm Hg
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 58 Pa
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0.44 mm Hg
- Transition / decomposition:
- no
- Conclusions:
- The vapour pressure of the test item was determined to be at 20°C (293K): 1.1 Pa (7.9 x10^-3 mmHg) and at 25°C (298K): 1.8 Pa (1.3x10^-2 mmHg) respectively.
- Executive summary:
The vapour pressure was determined using EU Method A.4, OECD TG 104 and EPA OPPTS 830.7950 by the thermogravimetric effusion method under GLP. Each reference substance was measured in duplicate by TGA using a temperature program that was specific for the substance. Plots of log vT obtained at elevated temperatures and 1/T were inter- or extrapolated to determine the log vT values at 20°C (log vT,20). The log vT,20 values were plotted against the logarithm of the vapour pressure at 20°C in Pascal units (log PT, 20). Linear regression analysis using the least squares method yielded an equation of log PT,20 = 1.17 × log vT,20 + 4.66. The coefficient of correlation (r) was > 0.99. The constants c and d specific for the experimental arrangement were 1.17 and 4.66, respectively. For the test item based on two separate experiments: the plot of the log PT of the test item as function of the reciprocal temperatures was performed. The equation of the curve was: log PT,20 = -3884 × 1/T + 13.27 (r = 0.992, n = 8). The vapour pressure of the test item was determined to be at 20°C (293K): 1.1 Pa (7.9 x10^-3 mmHg) and at 25°C (298K): 1.8 Pa (1.3x10^-2 mmHg) respectively.
Reference
The results of the isothermal TGA analysis for the test item and the vapour pressure at 20°C and 25°C are given in the following tables. Note: Experiment 1 was disregarded due to differences in sample size causing non-concordant results with Experiment 2 and 3. Since TGA is a kinetic method Experiment 1 is therefore non-comparable with Experiments 2 and 3 as highlighted by non-concordance between data-sets (Exp. 1 with smaller sample mass led to higher weight losses throughout).
Table 2.0 : Results of the isothermal TGA analysis
Experiment |
Temperature |
Weight loss |
νT |
log νT |
log PT |
PT |
2 |
50 |
10.84 |
1.29x10^-3 |
-2.89 |
1.27 |
19 |
|
60 |
24.04 |
2.87x10^-3 |
-2.54 |
1.68 |
47 |
|
70 |
45.02 |
5.37x10^-3 |
-2.27 |
2.00 |
99 |
|
80 |
74.03 |
8.84x10^-3 |
-2.05 |
2.25 |
1.8x10^2 |
3 |
50 |
8.716 |
1.04x10^-3 |
-2.98 |
1.16 |
14 |
|
60 |
22.36 |
2.67x10^-3 |
-2.57 |
1.64 |
44 |
|
70 |
43.12 |
5.15x10^-3 |
-2.29 |
1.97 |
94 |
|
80 |
70.90 |
8.46x10^-3 |
-2.07 |
2.23 |
1.7x10^2 |
Table 3.0 : Vapour pressure of the test item
Temperature |
log PT |
PT |
PT |
20 |
0.02 |
1.1 |
7.9x10^-3 |
25 |
0.25 |
1.8 |
1.3x10^-2 |
The plot of the log PT of the test item as function of the reciprocal temperatures was performed. The equation of the curve was: log PT,20 = -3884 × 1/T + 13.27 (r = 0.992, n = 8).
Description of key information
Vapour Pressure: 1.1 Pa at 20 °C and 1.8 Pa at 25 °C, EU Method A.4 : thermogravimetric effusion method, 2015
Key value for chemical safety assessment
- Vapour pressure:
- 1.8 Pa
- at the temperature of:
- 25 °C
Additional information
Key study : EU Method A.4, 2015 : The vapour pressure was determined using EU Method A.4, OECD TG 104 and EPA OPPTS 830.7950 by the thermogravimetric effusion method under GLP. Each reference substance was measured in duplicate by TGA using a temperature program that was specific for the substance. Plots of log vT obtained at elevated temperatures and 1/T were inter- or extrapolated to determine the log vT values at 20°C (log vT,20). The log vT,20 values were plotted against the logarithm of the vapour pressure at 20°C in Pascal units (log PT, 20). Linear regression analysis using the least squares method yielded an equation of log PT,20 = 1.17 × log vT,20 + 4.66. The coefficient of correlation (r) was > 0.99. The constants c and d specific for the experimental arrangement were 1.17 and 4.66, respectively. For the test item based on two separate experiments: the plot of the log PT of the test item as function of the reciprocal temperatures was performed. The equation of the curve was: log PT,20 = -3884 × 1/T + 13.27 (r = 0.992, n = 8). The vapour pressure of the test item was determined to be at 20°C (293K): 1.1 Pa (7.9 x10^-3 mmHg) and at 25°C (298K): 1.8 Pa (1.3x10^-2 mmHg) respectively.
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