Registration Dossier
Registration Dossier
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EC number: 407-920-5 | CAS number: 6390-69-8 CA 16-178
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study, a solubiliser was used
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
- Report date:
- 1989
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 3,3',5,5'-tetra-tert-butylbiphenyl-2,2'-diol
- EC Number:
- 407-920-5
- EC Name:
- 3,3',5,5'-tetra-tert-butylbiphenyl-2,2'-diol
- Cas Number:
- 6390-69-8
- Molecular formula:
- C28 H42 O2
- IUPAC Name:
- 3,3',5,5'-tetra-tert-butyl-[1,1'-biphenyl]-2,2'-diol
- Details on test material:
- - Name of test material (as cited in study report): TK 13219
- Lot/batch No.: A 88103/Z 1572R
- Purity: Lab. sample
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): bacteria sampled at a municipal sewage treatment plant (Therwil/Switzerland)
- Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 10.13 mg/L
- Based on:
- test mat.
- Initial conc.:
- 20.27 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Solubilising agent (type and concentration if used): Nonylphenol 10E05P0
- Test temperature: 22 ± 2 °C
SAMPLING
- Sampling frequency: on day 3, 8, 14, 17, 20, 24, 27 and 28
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 10
- Sampling time:
- 28 d
- Remarks on result:
- other: 10.13 mg test substance/l
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 2
- Sampling time:
- 28 d
- Remarks on result:
- other: 20.27 mg test substance/l
BOD5 / COD results
- Results with reference substance:
- Degradation rate of Aniline: 84.2% in 28 days
Applicant's summary and conclusion
- Interpretation of results:
- other: poorly biodegradable
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