Copper(II) carbonate-copper(II) hydroxide (1:1)

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Guideline study, no analytical dose verification. Most sensitive LC50 for the acute toxicity to fish as given in EHC 200 (1998). Soft water was used.

Data source

Reference

Reference 1

Reference Type:

publication

Title:

Comparative toxicity of inorganic contaminants released by placer mining to early life stages of salmonids.

Author:

Buhl KJ, Hamilton SJ

Year:

1990

Bibliographic source:

Ecotox Environm Safety 20: 325-342

Reference 2

Reference Type:

secondary source

Title:

Environmental Health Criteria (EHC) 200, Copper

Author:

WHO

Year:

1998

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: APHA (1988). E-729-88.

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Copper sulphate, pentahydrate

IUPAC Name:

Copper sulphate, pentahydrate

Constituent 2

Reference substance name:

7758-99-8

EC Number:

616-477-9

Cas Number:

7758-99-8

IUPAC Name:

7758-99-8

Details on test material:

- Analytical purity: "reagent grade or the highest purity available"

Sampling and analysis

Analytical monitoring:

no

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

other: Thymallus arcticus; Oncorhynchus mykiss

Details on test organisms:

TEST ORGANISM
- Common name: Arctic grayling
- Source: Clear state hatchery, Clear, Alaska
- Weight at study initiation (mean and range, SD): 0.34 g
- Feeding during test: no


ACCLIMATION
- Acclimation period: 24 h
- Acclimation conditions (same as test or not): yes

TEST ORGANISM
- Common name: Rainbow trout
- Source: Ennis National Fish Hatchery. Ennis, 1986 Montana
- Weight at study initiation (mean and range, SD): 0.6 g
- Feeding during test: no


ACCLIMATION
- Acclimation period: 24 h
- Acclimation conditions (same as test or not): yes

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

96 h

Test conditions

Hardness:

41.3 mg/L CaCO3 total hardness

Test temperature:

12±1°C

pH:

7.1-8.0

Nominal and measured concentrations:

6-10 test concentrations and control were tested

Reference substance (positive control):

no

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

0.003 mg/L

Nominal / measured:

nominal

Conc. based on:

element

Remarks:

Cu

Basis for effect:

mortality (fish)

Remarks on result:

other: Arctic grayling

Effect concentrations 2

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

0.014 mg/L

Nominal / measured:

nominal

Conc. based on:

element

Remarks:

Cu

Basis for effect:

mortality (fish)

Remarks on result:

other: Rainbow trout

Effect concentrations 3

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

0.004 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Remarks:

CH2Cu2O5

Basis for effect:

mortality (fish)

Remarks on result:

other: Arctic grayling

Effect concentrations 4

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

0.024 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Remarks:

CH2Cu2O5

Basis for effect:

mortality (fish)

Remarks on result:

other: Rainbow trout