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EC number: 273-761-1 | CAS number: 69012-64-2 Amorphous silicon dioxide particles from the volatilization and vaporization of furnace feed materials in the manufacture of ferrosilicon and silicon.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Study period:
- 26 Sep. 1991 - 27 Sep. 1991
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with acceptable restrictions (24 h instead of 48 h)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- yes
- Remarks:
- Test duration 24 h (acc. to the valid guideline of 04 April 1984) instead of 48 h (today) / In one test, the oxgen content was 4.4 mg/L at time 0, i.e. less than 60 % of saturation (not assumed to have affected the outcome).
- GLP compliance:
- yes
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- Aerosil 200: approx. 99.8 % (SiO2): CAS-Name: Silica, amorphous,
fumed, cryst.-free; CAS-No.: 112945-52-5
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: stirring for 20 h at 20 °C, followed by gross filtration (perlon wool) and microfiltration (1.7 µm and/or 1.2 µm)
- Eluate: no, filtrate
Filtration: through perlon wool, then through glass-fibre filter
A filtrate through 1.7 microfilter (still milky/cloudy)
B. filtrate through 1.7 and 1.2 µm microfilter (visibly clear)
- Differential loading: no, limit test with 1000 mg/L
- Controls: Synthetic medium from groundwater
Note: In two pre-tests, suspensions with 1000 and 10,000 mg/L SiO2 were used.
(see following entry: 02_Degussa AG 92-0139-DGO_pre-test, short-term toxicity to aquatic invertebrates)
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: see above
- Strain: --
- Source: laboratory culture
- Age at study initiation (mean and range, SD): <24 h
- Method of breeding: standard conditions according to principles of NPR 6503 (Nederlandse practijkrichtlijn of 1980)
- Feeding during test: no
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 24 h
- Post exposure observation period:
- none
Test conditions
- Hardness:
- 204 mg/L as CaCO3
- Test temperature:
- 20 +-1°C
- pH:
- 7.9 - 8.2
- Dissolved oxygen:
- 4.4 - 8.3 mg/L
- Salinity:
- not applicable
- Nominal and measured concentrations:
- 1000 mg/L SiO2 nominal
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 150-ml beaker
- Type: open
- Material, size, headspace, fill volume: glass, 50 mL headspace, 100 mL test volume
- Aeration: none
- Renewal rate of test solution (frequency/flow rate): none
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 8
- No. of vessels per pure control (replicates): 8 (synthetic medium)
- No. of vessels per filtration control (replicates): 8 (test in synthetic medium passed through perlon filter)
- Biomass loading rate: 5 animals/100 mL
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: groundwater with mineral salts supplemented (synthetic medium)
- Total organic carbon: 1.5 mg/L
- Alkalinity: no data
- Ca/mg ratio: 1.76
- Conductivity: no data
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16 h light, 8 h dark
- Light intensity: no data - Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EL50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks:
- 1/40 animals were immobile (see Results table below)
- Duration:
- 24 h
- Dose descriptor:
- EL0
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks:
- 1/40 animals were immobile (see Results table below)
- Details on results:
- - Mortality/immobility of control: none [0/40 animals]
- Mortality/immobility of treated animals: 1/40
Overall, 1/40 animals treated with the WAFs was found immobile after 24 h of exposure (2.5 %) (Report, Table B5 and B6 [Third (main) test]:
This consisted of two parallel series using clear or slightly milky solutions of the water-soluble fractions (WSF):
0/15 immobile animals (0 %) (assumed to relate to test medium microfiltrated 1.7 µm #)
1/25 immobile animals (4 %) (in the clear solution, assumed to relate to test medium microfiltrated 1.7 µm and 1.2 µm #)
- Abnormal responses: Based on pre-tests with suspensions, it is suspected that the immobility observed,
particularly with the 10,000 mg/l suspensions, could be attributed to physical effects.
(see following entry 02_Degussa 92-0139-DGO_pre-test.)
-----------------------------------
# Note: The wording under 3.5 (p. 14) says that "....there was one immobile animal (out of 25) in the clear solution prepared by filtration of the 1000 mg/L solution". This statement would correlate with the test medium microfiltrated at 1.7 and 1.2 µm, according to Report 3.4.3 (p. 14). However, the allocation of the results to the filtration conditions is inconsistent due to contradictory indexing in the Tables B5 and B6 of the Report (p.24/25). - Results with reference substance (positive control):
- not applicable
- Reported statistics and error estimates:
- not applicable
Any other information on results incl. tables
Number of mobile animals at given loadings of Aerosil 200
(from Report, Table B5):
Test 3 |
Loading [mg/L] |
|||
Time [h] |
||||
0 |
0*) |
1000*) |
1000**) |
|
0 |
40 |
40 |
25 |
15 |
24 |
40 |
40 |
24 |
15 |
*)filtered through perlon wool, followed by microfiltration of 1.7- and 1.2-µm pore size
**)filtered through perlon wool, followed by microfiltration of 1.7-µm pore size
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Aerosil 200 is not acutely toxic at a loading of >=1 000 mg/l.
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