Registration Dossier
Registration Dossier
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EC number: 700-589-0 | CAS number: 1369492-52-3
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated.
Key value for chemical safety assessment
Additional information
Acute toxicity of the mixture to aquatic organisms is derived from ecotoxicological information about the end-product and the by-product.
One GLP study according to OECD guideline 209 (1984) was performed with the end-product (including the impurity exceeding 1%). No effect on bacteria was observed.
Several non-GLP studies were performed with the by-products (ETAD Fermentation tube method) and the LC0 was determined to be > 2000 mg/L after 24h of exposure.
Toxicity to microorganisms is therefore not predicted for the test substance.
Reasons for read-across:
The substance was not tested for toxicity to microorganisms. The test substance is a mixture which consists mainly of the end-product (approximately 50%) and a by-product (approximately 30%) as well as of different impurities and isomers of the end-product (one exceeding 1%). Therefore, information about toxicity to microorganisms are derived from studies performed with the end-product and the by-product.
Performance and observations:
A GLP-compliant study was performed according to OECD guideline 209 (1984) with the end-product (including the impurity exceeding 1%).
The respective EC20 and EC50 are both higher than 100 mg/l, based on nominal concentrations. The test compound was added to the water without any suspension aid. No effect on the bacteria was observed
Toxicity to microorganisms of the by-product was evaluated in several non-GLP studies, according to ETAD Fermentation Tube method “Determination of damage to effluent bacteria by the Fermentation Tube Method”. The EC0 was determined to be higher than 2000 mg/L after a 24h exposure period.
Discussion:
The
end-product as well as the major by-product are not toxic to
microorganisms.
Toxic effects to microorganisms are therefore not predicted for the test substance.
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