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Diss Factsheets
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EC number: 248-096-5 | CAS number: 26896-48-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
(No)effect concentrations determined in a valid Earthworm Reprodution Test (OECD 222):
NOEC (reproduction, 56 d) = 59 mg/kg soil dw (nominal)
EC10 (reproduction, 56 d) = 39 mg/kg soil dw (nominal)
Key value for chemical safety assessment
- Long-term EC10, LC10 or NOEC for soil macroorganisms:
- 39 mg/kg soil dw
Additional information
An Earthworm Reproduction Test according to OECD 222 was performed with the test item (compliant with GLP). The study was performed using eight concentrations ranging from 1000 to 59 mg/kg dry soil.
No relevant mortality of adult animals after 28 days was observed, neither for the controls, nor for the treatment groups.
All surviving adult animals showed normal behaviour. Morphology of the surviving adult animals was normal. No relevant deviations of fresh weight change of surviving adults were observed for the treatment replicates compared to blank and solvent controls.
Inhibition of reproduction in the treatments in comparison to the combined controls was ob-served, ranging from 9.6 % to 80 %. All treatments except the lowest showed statistically significant inhibition of reproduction. All validity criteria were met.
The following results were obtained:
NOEC (reproduction, 56 d) = 59 mg/kg soil dw (nominal)
LOEC (reproduction, 56 d) = 88 mg/kg soil dw (nominal)
EC10 (reproduction, 56 d) = 39 mg/kg soil dw (nominal), 95% CI: 14 - 107.
The NOEC equals the lowest concentration applied, such that the EC10 is an extrapolated value. Nonetheless, as it is close to the lowest test item concentration applied and based on a sound concentration-effect relationship, the EC10 is regarded to be most relevant for chemical safety assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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