Registration Dossier
Registration Dossier
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EC number: 800-765-8 | CAS number: 1424149-03-0
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1991-07-08 to 1991-07-12
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP Guideline study, no deficiencies
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- sodium/triethanolamine 4-((2-hydroxyethyl)amino)-3-pentaproenyl-4-oxobutanoate
- EC Number:
- 800-765-8
- Cas Number:
- 1424149-03-0
- Molecular formula:
- C21H40NO4.1/2Na.1/2C6H15NO3
- IUPAC Name:
- sodium/triethanolamine 4-((2-hydroxyethyl)amino)-3-pentaproenyl-4-oxobutanoate
- Details on test material:
- Lot No. E 011 204 60
ca. 80% solid test item
ca. 10% Olefin
ca. 10% Water
brown liquid
pH 8.2 at 10 g/L
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- Stock solution 1000 mg/L (opaque but homogenous)
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- Source: Zoo-Stumpe, Hildesheim
Feed: Tetramin
Length: average 3.1 cm
Weight: average 0.36 g
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- not given
- Test temperature:
- 23 +/- 2 deg C
- pH:
- 7.82-8.03
- Dissolved oxygen:
- Saturation degree: 97-99%
- Nominal and measured concentrations:
- nominal: Control-10-18-32-58-100 mg/L
- Details on test conditions:
- Glas aquarium: 15L
10 fish per concentration
Light: diffus 12-16 h day light - Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 58 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95% CI 49-68 mg/L
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The registration substance was tested in an OECD 203 acute Fish test and from the results a LC50(96) of 58 mg/L was derived.
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