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EC number: 500-290-3 | CAS number: 103758-99-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
OECD 201, GLP and Klimisch 1 algal inhibition ErC50 4.34 mg/L, NOEC 0.5 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 4.34 mg/L
- EC10 or NOEC for freshwater algae:
- 0.5 mg/L
Additional information
The acute toxicity of the test item TOFA_DimerFA_TETA_PAA (batch no.: BB 001030 V1) to the unicellular freshwater green alga Pseudokirchneriella subcapitata was determined according to the principles of OECD Guideline for Testing 201 (2006) at Dr.U.Noack-Laboratorien,31157 Sarstedt, Germany. The aim of the study was to assess the effects on the growth rate in a medium containing 50% natural river water and 50% algal culture medium over a period of 72 hours.
The study was conducted under static conditions with an initial cell density of 5089 cells/mL.Five concentration levels were tested in a geometrical series with a dilution factor of 2 (nominal):0.500 - 1.00 - 2.00 - 4.00 - 8.00 mg/L. Three replicates were tested for each concentration level and six replicates for the control. Environmental conditions (pH and room temperature) were determined to be within the acceptable limits.
TOFA_DimerFA_TETA_PAA has low water solubility and may sorb to
organic and inorganic materials by different mechanisms. Due to these
properties the test item was difficult to test in artificial water (e.g.
sorption to the test organism and walls of the test vessel). Natural
river water contains particulate as well as dissolved organic carbon to
which the test item can sorb partially preventing that the test item
settles onto surfaces. The sorbed fraction of the test item was
difficult to extract from the test system which normally leads to low
analytical recoveries. Nevertheless the test item was present in the
test system and therefore available for exposure (dissolved in water and
sorbed).
No determinations of the test item concentrations were carried out. Preliminary investigations including the use of different analytical techniques have shown that no specific method was available that met the required sensitivity in the range of the test concentrations.
All effect levels are given based on nominal concentrations of TOFA_DimerFA_TETA_PAA.
The 72 h ErC50 of TOFA_DimerFA_TETA_PAA he freshwater green alga Pseudokirchneriella subcapitata was was 4.34 mg/L (95% confidence limits of 4.11 – 5.62 mg/L) and the corresponding NOEC was 0.5 mg/L.
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