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Diss Factsheets
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EC number: 610-992-2 | CAS number: 53378-52-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Short term toxicity to fish
In two independent 96-h acute toxicity studies, bluegills (Lepomis macrochirus) andrainbow trout (Oncorhynchus mykiss)were exposed to CT 473 -91 at nominal concentrations of 0 (water control), 5.6, 10, 18, 32 and 56 mg/L under static conditions.
The NOEC value was 18 mg/L for both studies. The LC50values were 42 and 30 mg/L (as nominal concentrations) for blue gills and rainbow trout, respectively.Both toxicity studies are classified as reliable without restrictions since they satisfy the guideline requirements for the fish acute toxicity study (OECD 203). However, water concentrations of test compound were not measured in either of the studies.
Based on a conservative approach, the study conducted with rainbow trout was choosen as the“key study” since it has the lowest LD50value.
Short term toxicity to aquatic invertebrates
In the first 48-h acute toxicity study, water fleas (Daphnia magna) were exposed to CT 473 -91 at nominal concentrations of 0 (water control), 32, 56, 100, 180 and 320 mg/L under static conditions.The NOEC value was 32 mg/L and the LC50was 42 mg/L (as nominal concentrations).
In the second 48-h acute toxicity study, water fleas (Daphnia magna) were exposed toS-10783at the followingnominal concentrations: control, 10, 22, 46, 100, 220 mg/L.The NOEC was 10 mg/L and the EC50 was 53 mg/L(as nominal concentrations).
Both toxicity studies are classified as reliable without restrictions since it satisfies the guideline requirements for the Daphnia acute toxicity study (OECD 202). However, water concentrations were only confirmed analytically in the second study. Consequently, the second study was selected as the “key study”.
Toxicity to aquatic algae and cyanobacteria
Green algae (Pseudokirchneriella subcapitata) were exposed to S-10783 at the following nominal concentrations: Control, 0.10, 1, 10, 100 mg/L. The NOEC and EC50 for both growth rate and biomass were >= 100 mg/L (as nominal concentrations).
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.