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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 201-919-1 | CAS number: 89-57-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Distribution modelling
Administrative data
- Endpoint:
- distribution modelling
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Title:
- No information
- Author:
- Anonymous
- Year:
- 2 012
- Bibliographic source:
- Episuite data (Epiweb 4.1)
Materials and methods
- Model:
- calculation according to Mackay, Level III
- Calculation programme:
- Epiweb 4.1
- Release year:
- 2 012
- Media:
- other: air-water-soil-sediment
Test material
- Reference substance name:
- 5-aminosalicylic acid
- EC Number:
- 201-919-1
- EC Name:
- 5-aminosalicylic acid
- Cas Number:
- 89-57-6
- Molecular formula:
- C7H7NO3
- IUPAC Name:
- 5-amino-2-hydroxybenzoic acid
Constituent 1
Results and discussion
Percent distribution in media
- Air (%):
- 0
- Water (%):
- 30.3
- Soil (%):
- 69.6
- Sediment (%):
- 0.1
Any other information on results incl. tables
Level III Fugacity Model (Full-Output):
=======================================
Chem Name : Benzoic acid, 5-amino-2-hydroxy-
Molecular Wt: 153.14
Henry's LC : 5.02e-012 atm-m3/mole (Henrywin program)
Vapor Press : 6.1e-008 mm Hg (Mpbpwin program)
Liquid VP : 6.49e-007 mm Hg (super-cooled)
Melting Pt : 129 deg C (Mpbpwin program)
Log Kow : 0.98 (Kowwin program)
Soil Koc : 10.4 (KOCWIN MCI method)
Mass Amount Half-Life Emissions
(percent) (hr) (kg/hr)
Air 0.000254 12.3 1000
Water 30.3 360 1000
Soil 69.6 720 1000
Sediment 0.0688 3.24e+003 0
Fugacity Reaction Advection Reaction Advection
(atm) (kg/hr) (kg/hr) (percent) (percent)
Air 3.28e-015 0.276 0.049 0.00921 0.00163
Water 9.57e-017 1.12e+003 584 37.5 19.5
Soil 4.43e-015 1.29e+003 0 43 0
Sediment 8.69e-017 0.284 0.0265 0.00946 0.000884
Persistence Time: 642 hr
Reaction Time: 797 hr
Advection Time: 3.3e+003 hr
Percent Reacted: 80.5
Percent Advected: 19.5
Half-Lives (hr), (based upon Biowin (Ultimate) and Aopwin):
Air: 12.3
Water: 360
Soil: 720
Sediment: 3240
Biowin estimate: 2.870 (weeks )
Advection Times (hr):
Air: 100
Water: 1000
Sediment: 5e+004
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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